15527

Glycine

meets analytical specification of Ph. Eur., BP, USP, 99-101% (based on anhydrous substance)

• Szinonimák: Aminoacetic acid, Aminoethanoic acid, Glycocoll
• Lineáris képlet: NH₂CH₂COOH
• CAS-szám: 56-40-6
• Molekulatömeg: 75.07
• Beilstein: 635782
• EC-szám: 200-272-2
• MDL-szám: MFCD00008131
• UNSPSC kód: 12352209
• eCl@ss: 32160406
• PubChem Substance ID: 57647473
• NACRES: NA.21

Tulajdonságok

• Minőségi szint: 200
• Teszt: 99-101% (based on anhydrous substance)
• form: crystalline powder
• minőség: meets analytical specification of Ph. Eur., BP, USP
• technika/technikák: IR spectroscopy: suitable
• szennyeződések: hydrolyzable substances, complies; organic volatile impurities, complies (GC); residual solvents, complies; ≤0.001% heavy metals (as Pb); ≤1.0% ninhydrin-positive substances
• izzítási maradék: ≤0.1% (as SO₄)
• veszteség: ≤0.2% loss on drying, 105 °C, 2 h
• szín: white
• pH: 5.9-6.4 (20 °C, 5%)
• pKa (25 °C): (1) 2.35, (2) 9.60; 2.35
• mp: 240 °C (dec.) (lit.)
• oldhatóság: H₂O: soluble 25 gm in 100 ml at 25 degrees c; H₂O: soluble 39.1 gm in 100 ml at 50 degrees c; alcohol: soluble 0.06 gm in 100 gm (Absolute); pyridine: soluble 164 parts; alcohol: very slightly soluble; diethyl ether: very slightly soluble
• anion nyomok: chloride (Cl^-): ≤50 mg/kg; sulfate (SO₄^2-): ≤50 mg/kg
• alkalmasság: complies for appearance of solution; complies for reaction against H₂SO₄; in accordance for identity (IR)
• SMILES string: NCC(O)=O
• InChI: 1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
• Nemzetközi kémiai azonosító kulcs: DHMQDGOQFOQNFH-UHFFFAOYSA-N
• Géninformáció: rat ... Grin2a(24409)

Leírás

Alkalmazás

Glycine was used for preparing platelets from whole-blood samples and study the stimulation of cytokine expression in leukocytes. It was used for biochemical and tolerance tests.

Biokémiai/fiziológiai hatások

Glycine has a pivotal role in lowering the plasma lipid levels in diabetic and obese patients by activating the CNS. During brain hypoxia glycine can stabilize the energetics disturbances in brain mitochondria. It also increases the in vitro development of porcine blastocysts when used along with glucose.

Inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.

Biztonsági adatok

• Tárolási osztály kódja: 11 - Combustible Solids
• WGK: WGK 1
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable
• Egyéni védőeszköz: Eyeshields, Gloves, type N95 (US)