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Fontos dokumentumok
A7470
Anti-c-Myc Agarose Affinity Gel antibody produced in rabbit
affinity isolated antibody
Szinonimák:
Anti-c-Myc
Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez
Összes fotó(1)
About This Item
UNSPSC kód:
12352203
NACRES:
NA.56
klón:
polyclonal
application:
IP
affinity chromatography
affinity chromatography
faj reaktivitás:
human
technika/technikák:
affinity chromatography: suitable
immunoprecipitation (IP): suitable
immunoprecipitation (IP): suitable
citations:
274
Javasolt termékek
![[Asn670, Leu671]-Amyloid β/A4 Precursor Protein 770 Fragment 667-676 trifluoroacetate salt ≥95% (HPLC), solid](/deepweb/assets/sigmaaldrich/product/images/296/089/259ad19e-25e1-4604-9077-8d4dbea518b6/640/259ad19e-25e1-4604-9077-8d4dbea518b6.jpg)
biológiai forrás
rabbit
Minőségi szint
konjugátum
agarose conjugate
antitest forma
affinity isolated antibody
antitest terméktípus
primary antibodies
klón
polyclonal
faj reaktivitás
human
analit kémiai osztály(ok)
proteins (c-Myc)
technika/technikák
affinity chromatography: suitable
immunoprecipitation (IP): suitable
kapacitás
≥10 nmol/mL binding capacity (c-Myc tagged fusion protein)
≥7 nmol/mL elution capacity (c-Myc tagged fusion protein)
UniProt elérési szám
tárolási hőmérséklet
2-8°C
Géninformáció
human ... MYC(4609)
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Általános leírás
The human c-Myc proto-oncogene belongs to MYC oncogene family and is the human cellular homolog of the avian v-Myc gene found in several leukemogenic retroviruses. c-Myc gene is localized on human chromosome 8q24.21. The two major domains of include the N-terminal box regions and the C-terminal basic-region with helix-loop-helix/leucine-zipper motif.
Egyediség
Anti-c-Myc recognizes an epitope located on c-Myc tagged fusion proteins.
Immunogén
synthetic peptide of the human p62c-Myc protein.
Alkalmazás
Anti-c-Myc Agarose Affinity Gel antibody produced in rabbit has been used in:
- chromatin immunoprecipitation (ChIP)
- co-immunoprecipitation
- western blotting
- immunofluorescence
- immunoprecipitation
Biokémiai/fiziológiai hatások
c-Myc proto-oncogene increased expression is observed in a variety of human tumors. Amplification of Myc gene locus is observed in angiosarcomas and translocation is implicated in Burkitt′s lymphoma. c-Myc is a master regulator and targets a wide variety of metabolic events. An epitope located within amino acid residues 410-419 (EQKLISEEDL) of human c-Myc has been widely used as a tag in many expression vectors, enabling the expression of proteins as c-Myc tagged fusion proteins. Anti-c-Myc agarose is useful in the purification of expressed c-Myc tagged fusion proteins in bacterial lysates or transfected cells.
Fizikai forma
Suspension of beaded agarose (1:1 v/v) in 0.01 M phosphate buffered saline containing 15 mM sodium azide.
Tárolás és stabilitás
For continuous use and extended storage, store at 2 °C to 8 °C. Do not freeze.
Egyéb megjegyzések
Jogi nyilatkozat
Unless otherwise stated in our catalog, our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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kapcsolódó termék
Tárolási osztály kódja
11 - Combustible Solids
WGK
WGK 1
Lobbanási pont (F)
Not applicable
Lobbanási pont (C)
Not applicable
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