MATFLAGELLIN

NEP Control Flagellin- PyroMAT^® System MAT

Non-endotoxin pyrogen control of flagellin for use in monocyte activation test

• Szinonimák: NEP, NEP Control
• UNSPSC kód: 41116130
• eCl@ss: 32160606
• NACRES: NA.24

Tulajdonságok

• Teszt: ≥95% (SDS-PAGE)
• Minőségi szint: 400
• használat: sufficient for 10 tests
• Jellemzők: Non-endotoxin pyrogen control of flagellin for use in monocyte activation test
• gyártó/kereskedő neve: PyroMAT^®
• alkalmazás(ok): pharmaceutical; pyrogen testing
• kompatibilitás: configured for PyroDetect System; configured for PyroMAT^® System
• kiszállítva: cooler
• tárolási hőmérséklet: −20°C
• alkalmasság: pyrogenic bacteria

Leírás

Általános leírás

The PyroMAT^® System uses cryopreserved Mono-Mac-6 (MM6) human monocytic cells as a source of monocytes. The response to a full range of pyrogens, including endotoxins and non-endotoxin pyrogens (NEPs)is determined by the measurement of interleukin-6 (IL-6) produced by the Mono-Mac-6 cells using ELISA.
NEP control flagellin is a preparation of flagellin from Salmonella typhimurium and supplied in a lyophilized form. Flagellin is a non-endotoxin pyrogen (NEP) that activates the TLR5 receptor of monocytes and can be used as a positive control with the PyroMAT^® System (Monocyte Activation Test for pyrogen detection).

Egyediség

TLR-5 agonist

Alkalmazás

NEP control of flagellin can be used as a positive control with the PyroMAT^® System. It is to be used for Product Specific Validation (PSV) and routine testing to show that the system can detect non-endotoxin pyrogen contaminants in pharmaceutical products.

Tulajdonságok és előnyök

Endotoxin-free product at concentration of use in MAT Purity: ≥ 95% (SDS-PAGE)

Tárolás és stabilitás

Store unopened vials at -20°C
Do not use unopened vials after expiration date
Store resuspended aliquots at -20°C
Shelf life of aliquots can be found on the technical datasheet

Jogi információk

PYROMAT is a registered trademark of Merck KGaA, Darmstadt, Germany

Biztonsági adatok

• Tárolási osztály kódja: 13 - Non Combustible Solids
• WGK: WGK 2
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable