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Merck

HTR1B

5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled

Synonimy:
5-HT1B, 5-HT1DB, HTR1D2, HTR1DB, S12
Gatunek:
Human HTR1B (3351), Mouse Htr1b (15551), Rat Htr1b (25075), chicken HTR1B (421858), Zebrafish htr1b (561647), dog HTR1B (403741), cow HTR1B (317707), Horse HTR1B (100009680), domestic cat HTR1B (100144391), Domestic Rabbit HTR1B (100009594) ...Więcej
Identyfikator UniProtKB:
P28222, Q4VAY7
Identyfikator genu:
  • Human(3351) Summary: The neurotransmitter serotonin (5-hydroxytryptamine; 5-HT) exerts a wide variety of physiologic functions through a multiplicity of receptors and may be involved in human neuropsychiatric disorders such as anxiety, depression, or migraine. These receptors consist of several main groups subdivided into several distinct subtypes on the basis of their pharmacologic characteristics, coupling to intracellular second messengers, and distribution within the nervous system (Zifa and Fillion, 1992 [PubMed 1359584]
  • Mouse(15551) 5-hydroxytryptamine (serotonin) receptor 1B
  • Rat(25075) 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
  • chicken(421858) 5-hydroxytryptamine (serotonin) receptor 1B
  • Zebrafish(561647) 5-hydroxytryptamine (serotonin) receptor 1B
  • dog(403741) 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
  • cow(317707) 5-hydroxytryptamine (serotonin) receptor 1B
  • Horse(100009680) 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
  • domestic cat(100144391) 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
  • Domestic Rabbit(100009594) 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
  • sheep(101111375) 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
  • domestic guinea pig(100135543) 5-hydroxytryptamine (serotonin) receptor 1B

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Small Molecule - Agonist

Numer produktu
Opis
Gatunek
N1415
Naratriptan hydrochloride, ≥98% (HPLC),
Gatunek
human
1457469
Naratriptan hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Gatunek
human
Y0000027
Sumatriptan for system suitability, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
S1198
Sumatriptan succinate, ≥98% (HPLC), solid,
Gatunek
human
SML0248
Zolmitriptan, ≥98% (HPLC),
Gatunek
human

Small Molecule - Allosteric Modulator

Numer produktu
Opis
Gatunek
D9190
DCEBIO, ≥98% (HPLC), solid,
Gatunek
human

Small Molecule - Antagonist

Numer produktu
Opis
Gatunek
G5793
GR 127935 hydrochloride hydrate, >98% (HPLC), powder,
Gatunek
human
M149
Methiothepin mesylate salt, ≥98% (HPLC), solid,
Gatunek
human
P8688
(S)-(−)-Propranolol hydrochloride, ≥98% (TLC), powder,
Gatunek
human
T6154
Trazodone hydrochloride, ≥99% (HPLC), powder,
Gatunek
human
M137
Methysergide maleate salt, solid,
Gatunek
human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
SAB4501470
Anti-5-HT-1B antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunofluorescence
immunohistochemistry
SAB4501471
Anti-HTR1B antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunofluorescence
western blot
SAB2500924
Anti-Serotonin Receptor 1B/HTR1B antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reaktywność gatunkowa
canine, human, mouse, rat
Zastosowanie
ELISA
western blot

Small Molecule - Blocker

Numer produktu
Opis
Gatunek
P8688
(S)-(−)-Propranolol hydrochloride, ≥98% (TLC), powder,
Gatunek
human
T6154
Trazodone hydrochloride, ≥99% (HPLC), powder,
Gatunek
human
T3146
Trimipramine maleate salt, ≥98% (TLC), powder,
Gatunek
human
Z101
Zimelidine dihydrochloride, solid,
Gatunek
human

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
T6154
Trazodone hydrochloride, ≥99% (HPLC), powder,
Gatunek
human
F1553
S-(+)-Fluoxetine hydrochloride, ≥98% (HPLC), solid,
Gatunek
human
F1678
R-(−)-Fluoxetine hydrochloride, >98% (HPLC), solid,
Gatunek
human
S6319
Sertraline hydrochloride, ≥98% (HPLC),
Gatunek
human
F2802
Fluvoxamine maleate, solid,
Gatunek
human

Small Molecule - Metabolite

Numer produktu
Opis
Gatunek
H8876
5-Hydroxyindole-3-acetic acid, ≥98% (HPLC), crystalline,
Gatunek
human

Small Molecule - Precursor

Numer produktu
Opis
Gatunek
H9772
5-Hydroxy-L-tryptophan, powder,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
EMU044151
MISSION® esiRNA, targeting mouse Htr1b,
Gatunek
mouse