SML0248

Zolmitriptan

≥98% (HPLC)

• Synonim(y): (4S)-4-((3-(2-(Dimethylamino)ethyl)-1H-indol-5-yl)methyl)-2-oxazolidinone, (S)-4-((3-(2-(Dimethylamino)ethyl)indol-5-yl)methyl)-2-oxazolidinone, 311C90
• Wzór empiryczny (zapis Hilla): C₁₆H₂₁N₃O₂
• Numer CAS: 139264-17-8
• Masa cząsteczkowa: 287.36
• NACRES: NA.77
• PubChem Substance ID: 329825258
• UNSPSC Code: 12352200
• MDL number: MFCD00871503
• Assay: ≥98% (HPLC)
• Form: powder

Właściwości

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• optical activity: [α]/D -3 to -8°, c = 1 in methanol
• color: white to beige
• solubility: DMSO: ≥5 mg/mL
• storage temp.: 2-8°C
• SMILES string: CN(C)CCc1c[nH]c2ccc(C[C@H]3COC(=O)N3)cc12
• InChI: 1S/C16H21N3O2/c1-19(2)6-5-12-9-17-15-4-3-11(8-14(12)15)7-13-10-21-16(20)18-13/h3-4,8-9,13,17H,5-7,10H2,1-2H3,(H,18,20)/t13-/m0/s1
• InChI key: ULSDMUVEXKOYBU-ZDUSSCGKSA-N
• Gene Information: human ... HTR1B(3351), HTR1D(3352)

Opis

Application

Zolmitriptan has been used as a 5-hydroxytryptamine receptor 1B (5-HT_1B/D) activator to treat grafts to study its effects on the morphology of the ectopic eye.

Zolmitriptan has been used to induce hyper-innervation of transplants.

Biochem/physiol Actions

Zolmitriptan is a potent, selective. centrally and peripherally acting 5HT1B/1D receptor agonist.

Zolmitriptan is a selective serotonin receptor agonist of the 5HT1B and 5HT1D subtypes, both centrally and peripherally. It has been used clinically for the acute treatment of migraine attacks with or without aura and cluster headaches.

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable