M149

Methiothepin mesylate salt

≥98% (HPLC), solid

• Synonim(y): 1-[10,11-Dihydro-8-(methylthio)dibenzo[b,f]thiepin-10-yl]-4-methylpiperazine mesylate salt, Metitepine mesylate salt
• Wzór liniowy: C₂₀H₂₄N₂S₂ · CH₃SO₃H
• Numer CAS: 74611-28-2
• Masa cząsteczkowa: 452.65
• NACRES: NA.77
• PubChem Substance ID: 24278104
• UNSPSC Code: 12352200
• MDL number: MFCD00153831
• Assay: ≥98% (HPLC)
• Form: solid
• Storage condition: desiccated

Właściwości

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: solid
• storage condition: desiccated
• color: white
• solubility: H₂O: 13 mg/mL
• SMILES string: CS(O)(=O)=O.CSc1ccc2Sc3ccccc3CC(N4CCN(C)CC4)c2c1
• InChI: 1S/C20H24N2S2.CH4O3S/c1-21-9-11-22(12-10-21)18-13-15-5-3-4-6-19(15)24-20-8-7-16(23-2)14-17(18)20;1-5(2,3)4/h3-8,14,18H,9-13H2,1-2H3;1H3,(H,2,3,4)
• InChI key: CZMDZGZYKOGLJY-UHFFFAOYSA-N
• Gene Information: human ... HTR1A(3350), HTR1B(3351), HTR1D(3352), HTR1E(3354), HTR1F(3355), HTR6(3362), HTR7(3363)

Opis

General description

Methiothepin belongs to a new class of dibenzothiophenes. Methiothepin possesses neuroleptic activity.

Application

Methiothepin mesylate salt has been used to explore the relationship between circulating cells and the niche. It has also been used in serotonin (5-HT) and antagonists in vivo bioassays and in in vivo antagonist and lipopolysaccharide stimulations.

Biochem/physiol Actions

Methiothepin mesylate salt is a 5-HT₁, 5-HT₆, 5-HT₇ serotonin receptor antagonist, which blocks serotonin autoreceptors.

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)