1370280

Loratadine Related Compound A

United States Pharmacopeia (USP) Reference Standard

• Szinonimák: Desloratadine, 8-Chloro-6,11-dihydro-11-(4-piperidinylidene)-5H- benzo[5,6]cyclohepta[1,2,b]pyridine, Clarinex^®, NSC 675447
• Tapasztalati képlet (Hill-képlet): C₁₉H₁₉ClN₂
• CAS-szám: 100643-71-8
• Molekulatömeg: 310.82
• MDL-szám: MFCD00871949
• UNSPSC kód: 41116107
• PubChem Substance ID: 329750257
• NACRES: NA.24

Tulajdonságok

• grade: pharmaceutical primary standard
• API-család: loratadine
• gyártó/kereskedő neve: USP
• alkalmazás(ok): pharmaceutical (small molecule)
• Formátum: neat
• SMILES string: Clc1ccc2c(CCc3cccnc3\C2=C4\CCNCC4)c1
• InChI: 1S/C19H19ClN2/c20-16-5-6-17-15(12-16)4-3-14-2-1-9-22-19(14)18(17)13-7-10-21-11-8-13/h1-2,5-6,9,12,21H,3-4,7-8,10-11H2
• Nemzetközi kémiai azonosító kulcs: JAUOIFJMECXRGI-UHFFFAOYSA-N
• Géninformáció: human ... HRH1(3269)

Leírás

Általános leírás

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Alkalmazás

Loratadine Related Compound A USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.
Also, for use with USP monographs such as:

• Loratadine Orally Disintegrating Tablets
• Loratadine Chewable Tablets
• Loratadine Capsules

Biokémiai/fiziológiai hatások

A non-sedating H₁-receptor antagonist, free from antimuscarinic/anticholinergic effects. It has novel antiallergic and anti-inflammatory effects.

Desloratadine is a selective and nonsedating histamine H1 receptor antagonist, an active metabolite of loratadine (Claritin), used to relieve hay fever and allergy symptoms with less drowsiness than other antihistamines; does not significantly inhibits cardiac K+ channels at clinically achievable blood levels. Free from antimuscarinic/anticholinergic effects.

Analízis megjegyzés

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Egyéb megjegyzések

Sales restrictions may apply.

Jogi információk

Clarinex is a registered trademark of Schering Corp.

Biztonsági adatok

• Tárolási osztály kódja: 11 - Combustible Solids
• WGK: WGK 1
• Lobbanási pont (F): 390.2 °F - Pensky-Martens closed cup
• Lobbanási pont (C): 199 °C - Pensky-Martens closed cup