Ugrás a tartalomra
Merck
Összes fotó(5)

Key Documents

View All Documentation

T1147

Sigma-Aldrich

apo-Transferrin human

powder, BioReagent, suitable for cell culture, ≥98% (agarose gel electrophoresis)

Szinonimák:

Human transferrin, Siderophilin

Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez
Összes fotó(5)

About This Item

CAS-szám:
11096-37-0
EC-szám:
234-318-8
MDL-szám:
MFCD00130536
UNSPSC kód:
12352202
NACRES:
NA.75

biológiai forrás

human plasma

Minőségi szint

200

termékcsalád

BioReagent

Teszt

≥98% (agarose gel electrophoresis)

form

powder

molekulatömeg

76-81 kDa

koncentráció

~25 mM

technika/technikák

cell culture | mammalian: suitable

szennyeződések

HIV and HBsAg, source material tested negative
≤0.005% iron

oldhatóság

H2O: 50 mg/mL

UniProt elérési szám

P02787

kiszállítva

wet ice

tárolási hőmérséklet

−20°C

Géninformáció

human ... TF(7018)

Looking for similar products? Látogasson el ide Útmutató a termékösszehasonlításhoz

Alkalmazás

Apo-Transferrin human can be supplemented with iron or used to bind free iron present in media. It is also used to transport iron into mammalian cells.

Biokémiai/fiziológiai hatások

Transferrin is the primary iron binding and cell delivery molecule present in serum. Serum-free cell culture systems require a delivery format for iron. Transferrin is the preferential delivery form of iron because cells process transferrin bound iron in a physiologically appropriate way through transferrin receptors on the cell surface. Human apo-transferrin is a high affinity transferrin that can be used with a wide range of cells types. Apo-transferrin can be loaded with iron prior to use or added directly to an iron containing medium.

Egyéb megjegyzések

Non-heme iron-transport protein.

Jogi nyilatkozat

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Tárolási osztály kódja

11 - Combustible Solids

WGK

WGK 3

Analitikai tanúsítványok (COA)

Analitikai tanúsítványok (COA) keresése a termék sarzs-/tételszámának megadásával. A sarzs- és tételszámok a termék címkéjén találhatók, a „Lot” vagy „Batch” szavak után.

Már rendelkezik ezzel a termékkel?

Az Ön által nemrégiben megvásárolt termékekre vonatkozó dokumentumokat a Dokumentumtárban találja.

Dokumentumtár megtekintése

Giang D Nguyen et al.
PloS one, 8(8), e72698-e72698 (2013-08-24)
Huntington's disease (HD) is a neurodegenerative disease caused by abnormal polyglutamine expansion in the huntingtin protein (Htt). Although both Htt and the HD pathogenic mutation (mHtt) are implicated in early developmental events, their individual involvement has not been adequately explored.
Giang D Nguyen et al.
PloS one, 9(5), e96858-e96858 (2014-05-08)
H1 linker histone proteins are essential for the structural and functional integrity of chromatin and for the fidelity of additional epigenetic modifications. Deletion of H1c, H1d and H1e in mice leads to embryonic lethality by mid-gestation with a broad spectrum
Kathleen N O'Guin et al.
ASN neuro, 6(1), e00135-e00135 (2014-01-31)
The molecular requirements for human myelination are incompletely defined, and further study is needed to fully understand the cellular mechanisms involved during development and in demyelinating diseases. We have established a human co-culture model to study myelination. Our earlier observations
William J Buchser et al.
PloS one, 7(6), e38101-e38101 (2012-06-16)
Trauma to the spinal cord and brain can result in irreparable loss of function. This failure of recovery is in part due to inhibition of axon regeneration by myelin and chondroitin sulfate proteoglycans (CSPGs). Peripheral nervous system (PNS) neurons exhibit
Ayumu Suzuki et al.
Nature communications, 7, 11056-11056 (2016-03-31)
Meiosis is a unique process that allows the generation of reproductive cells. It remains largely unknown how meiosis is initiated in germ cells and why non-germline cells do not undergo meiosis. We previously demonstrated that knockdown of Max expression, a
View All Related Papers

Cikkek

Transferrin in Cell Culture

Understand how transferrin affects serum-free cell culture systems, crucial for biomanufacturing heterologous proteins like monoclonal antibodies.

Tudóscsoportunk valamennyi kutatási területen rendelkezik tapasztalattal, beleértve az élettudományt, az anyagtudományt, a kémiai szintézist, a kromatográfiát, az analitikát és még sok más területet.

Lépjen kapcsolatba a szaktanácsadással