Összes fotó(1)
Fontos dokumentumok
M0757
Isopropyl myristate
≥90% (GC)
Szinonimák:
Isopropyl tetradecanoate, Myristic acid isopropyl ester
Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez
Összes fotó(1)
About This Item
Lineáris képlet:
CH3(CH2)12COOCH(CH3)2
CAS-szám:
Molekulatömeg:
270.45
Beilstein:
1781127
EC-szám:
MDL-szám:
UNSPSC kód:
12352211
PubChem Substance ID:
NACRES:
NA.25
Javasolt termékek
biológiai forrás
synthetic (organic)
Minőségi szint
Teszt
≥90% (GC)
Forma
liquid
törésmutató
n20/D 1.434 (lit.)
bp
193 °C/20 mmHg (lit.)
mp
~3 °C (lit.)
sűrűség
0.85 g/mL at 25 °C (lit.)
funkcionális csoport
ester
lipidtípus
saturated FAs
kiszállítva
ambient
tárolási hőmérséklet
2-8°C
SMILES string
CCCCCCCCCCCCCC(=O)OC(C)C
InChI
1S/C17H34O2/c1-4-5-6-7-8-9-10-11-12-13-14-15-17(18)19-16(2)3/h16H,4-15H2,1-3H3
Nemzetközi kémiai azonosító kulcs
AXISYYRBXTVTFY-UHFFFAOYSA-N
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Alkalmazás
- Formulation design and development of matrix diffusion controlled transdermal drug delivery of glimepiride.: This study discusses the design of a transdermal drug delivery system for glimepiride, utilizing matrix diffusion mechanisms potentially incorporating Isopropyl Myristate to enhance permeation (Akram et al., 2018).
- Investigation of microemulsion and microemulsion gel formulations for dermal delivery of clotrimazole.: This article evaluates formulations incorporating Isopropyl Myristate for enhanced dermal delivery of clotrimazole, highlighting its role in improving drug solubility and skin absorption rates (Zhang and Michniak-Kohn, 2018).
Biokémiai/fiziológiai hatások
Isopropyl myristate (myristic acid isopropyl ester) is used to change the physicochemical characteristics of microsheres such as poly(lactic-co-glycolic acid) (PLGA) microspheres. Isopropyl myristate is used as a oil phase component in the formulation of microemulsion systems.
Tárolási osztály kódja
10 - Combustible liquids
WGK
awg
Lobbanási pont (F)
>302.0 °F
Lobbanási pont (C)
> 150 °C
Egyéni védőeszköz
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
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Eva Abramov et al.
Journal of colloid and interface science, 591, 363-372 (2021-02-24)
Modified microemulsions (MEs), termed by us nanodomains (NDs), seem to be suitable vehicles for dermal drug delivery due to their high surface area and the interface enriched with membrane recognizing agents, penetration enhancers, and other components. However, liquid nanodomains do
Mahendra Singh et al.
Journal of controlled release : official journal of the Controlled Release Society, 328, 895-916 (2020-10-19)
The eye is the specialized part of the body and is comprised of numerous physiological ocular barriers that limit the drug absorption at the action site. Regardless of various efforts, efficient topical ophthalmic drug delivery remains unsolved, and thus, it
Qian Zhang et al.
Pharmaceutical research, 30(1), 32-40 (2012-08-28)
In principle, maximum transepidermal fluxes of solutes should be similar for different vehicles, except when the solute or vehicle modifies the skin. Here we estimated maximum flux, stratum corneum solubility, diffusivity and permeability coefficient for a range of similarly sized
Ji Zhang et al.
International journal of pharmaceutics, 421(1), 34-44 (2011-10-01)
In this study, microemulsion microstructures, key formulation variables, and their relationship to drug transdermal permeation enhancement were investigated. A microemulsion system with high water soluble capacity was developed, using isopropyl myristate, Labrasol, and Cremophor EL as oil, surfactant, and co-surfactant
Fan Yang et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 82(1), 158-163 (2012-06-21)
Transdermal delivery of methotrexate (MTX) was investigated by using the solid-in-oil (S/O) technique. Because MTX was coated with nonionic surfactant molecules, the resulting complex was easy to dissolve in various organic solvents and provided a transparent solution in isopropyl myristate
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