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Merck
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E1282

Sigma-Aldrich

Anti-Epidermal Growth Factor Receptor antibody produced in goat

affinity isolated antibody, lyophilized powder

Szinonimák:

Anti-Egfr, Anti-Erbb, Anti-Errp, Anti-Wa5

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About This Item

MDL-szám:
MFCD00162282
UNSPSC kód:
51111800
NACRES:
NA.41

biológiai forrás

goat

Minőségi szint

100

konjugátum

unconjugated

antitest forma

affinity isolated antibody

antitest terméktípus

primary antibodies

klón

polyclonal

form

lyophilized powder

faj reaktivitás

mouse

technika/technikák

immunohistochemistry: 5-15 μg/mL
western blot: 0.1-0.25 μg/mL

UniProt elérési szám

Q01279

tárolási hőmérséklet

−20°C

célzott transzláció utáni módosítás

unmodified

Géninformáció

mouse ... Egfr(13649)

Related Categories

Immunogen

purified, NSO cell-derived recombinant mouse epidermal growth factor receptor extracellular domain.

Biokémiai/fiziológiai hatások

EGFR is a transmembrane glycoprotein that binds to the EGF family. It is a pivotal regulator of cell proliferation, growth, differentiation and DNA repair after radiation-induced damage. Mutations in the gene encoding EGFR are associated with a number of malignancies including lung cancer and colorectal cancer.

Fizikai forma

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.

Jogi nyilatkozat

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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E1282

Anti-Epidermal Growth Factor Receptor antibody produced in goat, affinity isolated antibody, lyophilized powder

E0532

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Tárolási osztály kódja

13 - Non Combustible Solids

WGK

WGK 1

Lobbanási pont (F)

Not applicable

Lobbanási pont (C)

Not applicable

Egyéni védőeszköz

Eyeshields, Gloves, type N95 (US)

Analitikai tanúsítványok (COA)

Analitikai tanúsítványok (COA) keresése a termék sarzs-/tételszámának megadásával. A sarzs- és tételszámok a termék címkéjén találhatók, a „Lot” vagy „Batch” szavak után.

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Az Ön által nemrégiben megvásárolt termékekre vonatkozó dokumentumokat a Dokumentumtárban találja.

Dokumentumtár megtekintése

Tai Hoon Kim et al.
FEBS letters, 585(1), 121-127 (2010-11-26)
Cuticle formation and molting are critical for the development of Caenorhabditis elegans. To understand cuticle formation more clearly, we screened for suppressors in transgenic worms that expressed dominant ROL-6 collagen proteins. The suro-1 mutant, which is mild dumpy, exhibited a
Takahiro Nakamura et al.
The Journal of clinical investigation, 124(1), 385-397 (2013-12-10)
Corneal integrity and transparency are indispensable for good vision. Cornea homeostasis is entirely dependent upon corneal stem cells, which are required for complex wound-healing processes that restore corneal integrity following epithelial damage. Here, we found that leucine-rich repeats and immunoglobulin-like
Zhilian Li et al.
Diabetes, 67(9), 1847-1857 (2018-07-01)
Previous studies by us and others have indicated that renal epidermal growth factor receptors (EGFR) are activated in models of diabetic nephropathy (DN) and that inhibition of EGFR activity protects against progressive DN in type 1 diabetes. In this study
Ming-Zhi Zhang et al.
Journal of the American Society of Nephrology : JASN, 30(9), 1659-1673 (2019-07-12)
Sex differences mediating predisposition to kidney injury are well known, with evidence indicating lower CKD incidence rates and slower decline in renal function in nondiabetic CKD for premenopausal women compared with men. However, signaling pathways involved have not been elucidated
Thu H Truong et al.
Biochemistry, 51(50), 9954-9965 (2012-11-29)
Epidermal growth factor receptor (EGFR) exemplifies the family of receptor tyrosine kinases that mediate numerous cellular processes, including growth, proliferation, and differentiation. Moreover, gene amplification and EGFR mutations have been identified in a number of human malignancies, making this receptor
View All Related Papers

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