ALD00604

(+)-PSI Reagent

95%

• Szinonimák: (+)-Ψ, (2R,3aR,6S,7aR)-3a-Methyl-2-((perfluorophenyl)thio)-6-(prop-1-en-2-yl)hexahydrobenzo[d][1,3,2]oxathiaphosphole 2-sulfide, Phosphorus-Sulfur Incorporation Reagent
• Tapasztalati képlet (Hill-képlet): C₁₆H₁₆F₅OPS₃
• CAS-szám: 2245335-71-9
• Molekulatömeg: 446.46
• MDL-szám: MFCD32068366
• UNSPSC kód: 12352101
• NACRES: NA.22

Tulajdonságok

• Teszt: 95%
• Forma: powder or crystals
• mp: 102-107 °C
• SMILES string: Fc1c(c(c(c(c1F)F)S[P]2(=S)S[C@]3([C@H](O2)C[C@H](CC3)C(=C)C)C)F)F
• Nemzetközi kémiai azonosító kulcs: YPYCUYPOHPPYAS-DWBMIXFYSA-N

Leírás

Alkalmazás

Air- and moisture-tolerant, this (+)-PSI Reagent was developed in the Baran lab for stereocontrolled synthesis of phosphorothioate oligonucleotides. The enantiomer, (−)-PSI Reagent, is also available (cat# ALD00602).
The PSI Reagents open access to thiophosphate-based nucleotide molecules with therapeutic promise as demonstrated by the Baran lab in the preparation of pure stereoisomers of cyclic dinucleotides (CDNs) and antisense oligonucleotides (ASOs).

Learn more about PI and PSI reagents

Egyéb megjegyzések

Unlocking P(V): Reagents for chiral phosphorothioate synthesis

PSI on OpenFlask

Jogi információk

PCT/US2019/027256; U.S. Nonprovisional Patent Application #16/382,692

Biztonsági adatok

• Tárolási osztály kódja: 11 - Combustible Solids
• WGK: WGK 3
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable