AB9568
Anti-Neurofilament L Antibody
serum, Chemicon®
Szinonimák:
Anti-CMT1F, Anti-CMT2E, Anti-CMTDIG, Anti-NF-L, Anti-NF68, Anti-NFL, Anti-PPP1R110
Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez
Méret kiválasztása
50 μL
144 000,00 Ft
144 000,00 Ft
Készletenrészletek
Az adott célhoz egy rekombináns, tartósítószer-mentes antitest elérhető. Próbálja meg ezt: ZRB1445
Megrendelés igénylése nagy tételben
Összes fotó(2)
Méret kiválasztása
Nézet módosítása
50 μL
144 000,00 Ft
About This Item
UNSPSC kód:
12352203
eCl@ss:
32160702
NACRES:
NA.41
144 000,00 Ft
Készletenrészletek
Az adott célhoz egy rekombináns, tartósítószer-mentes antitest elérhető. Próbálja meg ezt: ZRB1445
Megrendelés igénylése nagy tételben
Javasolt termékek
biológiai forrás
rabbit
Minőségi szint
antitest forma
serum
antitest terméktípus
primary antibodies
klón
polyclonal
faj reaktivitás
rat, pig, human, bovine, feline, canine, mouse
gyártó/kereskedő neve
Chemicon®
technika/technikák
immunocytochemistry: suitable
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
western blot: suitable
NCBI elérési szám
UniProt elérési szám
kiszállítva
dry ice
célzott transzláció utáni módosítás
unmodified
Géninformáció
human ... NEFL(4747)
Általános leírás
Neurofilaments are a type of intermediate filament that serve as major elements of the cytoskeleton supporting the axon cytoplasm. They are the most abundant fibrillar components of the axon, being on average 3-10 times more frequent than axonal microtubules. Neurofilaments (10 nm in dia.) are built from three intertwined protofibrils which are themselves composed of two tetrameric protofilament complexes of monomeric proteins. The neurofilament triplet proteins (68/70, 160, and 200 kDa) occur in both the central and peripheral nervous system and are usually neuron specific. The 68/70 kDa NF-L protein can self-assemble into a filamentous structure, however the 160 kDa NF-M and 200 kDa NF-H proteins require the presence of the 68/70 kDa NF-L protein to co-assemble. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas and neuroblastomas stain positively for neurofilaments. Although typically restricted to neurons, neurofilaments have been detected in paragangliomas and adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and oat cell carcinomas of the lung also express neurofilaments.
Egyediség
Recognizes Neurofilament-Light (NF-L)
Immunogén
Purified porcine NF-L
Alkalmazás
Detect Neurofilament L using this Anti-Neurofilament L Antibody validated for use in IC, IH, IH(P) & WB.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neurofilament & Neuron Metabolism
Neuronal & Glial Markers
Neurofilament & Neuron Metabolism
Neuronal & Glial Markers
Western Blot Analysis:
1:1000 dilution of a previous lot detected NEUROFILAMENT L on 10 μg of mouse brain lysates.
Immunocytochemistry:
A 1:200-1:500 dilution of a previous lot was used in IC.
Optimal working dilutions must be determined by the end user.
1:1000 dilution of a previous lot detected NEUROFILAMENT L on 10 μg of mouse brain lysates.
Immunocytochemistry:
A 1:200-1:500 dilution of a previous lot was used in IC.
Optimal working dilutions must be determined by the end user.
Minőség
Immunohistochemistry(paraffin) Analysis:
Neurofilament-L (cat. # AB9568) staining on Normal Cerebellum. Tissue pretreated with Citrate, pH 6.0. This lot of antibody was diluted to 1:800, using IHC-Select Detection with HRP-DAB. Immunoreactivity is seen as fiber-like- staining (brown) around a Purkinje cells.
Optimal Staining With EDTA Buffer, pH 8.0, Epitope Retrieval: Human Cerebellum
Neurofilament-L (cat. # AB9568) staining on Normal Cerebellum. Tissue pretreated with Citrate, pH 6.0. This lot of antibody was diluted to 1:800, using IHC-Select Detection with HRP-DAB. Immunoreactivity is seen as fiber-like- staining (brown) around a Purkinje cells.
Optimal Staining With EDTA Buffer, pH 8.0, Epitope Retrieval: Human Cerebellum
Cél megnevezése
68-70 kDa
Kapcsolódás
Replaces: 04-1112
Fizikai forma
Rabbit serum. Contains no preservative.
Unpurified
Tárolás és stabilitás
Stable for 1 year at -20ºC from date of receipt.
Analízis megjegyzés
Control
Brain tissue
Brain tissue
Egyéb megjegyzések
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Jogi információk
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Jogi nyilatkozat
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Próbálja ki a Termékválasztó eszköz. eszközt
javasolt
Tárolási osztály kódja
11 - Combustible Solids
WGK
WGK 1
Lobbanási pont (F)
Not applicable
Lobbanási pont (C)
Not applicable
Analitikai tanúsítványok (COA)
Analitikai tanúsítványok (COA) keresése a termék sarzs-/tételszámának megadásával. A sarzs- és tételszámok a termék címkéjén találhatók, a „Lot” vagy „Batch” szavak után.
Már rendelkezik ezzel a termékkel?
Az Ön által nemrégiben megvásárolt termékekre vonatkozó dokumentumokat a Dokumentumtárban találja.
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Samantha L Eaton et al.
PloS one, 8(8), e72457-e72457 (2013-09-12)
Western blotting has been a key technique for determining the relative expression of proteins within complex biological samples since the first publications in 1979. Recent developments in sensitive fluorescent labels, with truly quantifiable linear ranges and greater limits of detection
Srinivasu Kallakuri et al.
Journal of neurosciences in rural practice, 6(4), 481-487 (2016-01-12)
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