1.05980

D-Mannitol

EMPROVE^® ESSENTIAL, Ph. Eur., BP, ChP, JP, USP, FCC, E 421

• Szinonimák: Mannite
• Tapasztalati képlet (Hill-képlet): C₆H₁₄O₆
• CAS-szám: 69-65-8
• Molekulatömeg: 182.17
• Beilstein: 1721898
• MDL-szám: MFCD00064287
• UNSPSC kód: 12352201
• E szám: E421
• EC index szám: 200-711-8

Tulajdonságok

• Ügynökség: BP; ChP; JP; Ph. Eur.; USP
• Minőségi szint: 500
• szab. megfelelőség: FCC
• termékcsalád: EMPROVE^® ESSENTIAL
• form: fine powder
• öngyulladási hőmérséklet: 410 °C
• hatékonyság: 13500 mg/kg LD₅₀, oral (Rat)
• minőség: E 421
• részecskeméret: (see specification)
• pH: 5-7 (20 °C, 100 g/L in H₂O)
• bp: 290-295 °C/4 hPa
• mp: 167-170 °C (lit.)
• oldhatóság: 213 g/L
• alkalmazás(ok): liquid formulation; pharmaceutical; semi-solid formulation; solid formulation
• tárolási hőmérséklet: 2-25°C
• SMILES string: OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO
• InChI: 1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4-,5-,6-/m1/s1
• Nemzetközi kémiai azonosító kulcs: FBPFZTCFMRRESA-KVTDHHQDSA-N

Leírás

Általános leírás

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our EMPROVE^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Alkalmazás

Mannitol is widely used in pharmaceutical formulations and food applications, mainly as diluent and bulking agent in solid oral formulations such as tablets. For mannitols with DC properties or for a product specifically developed for wet granulation, please explore the Parteck^® range of products.

Biokémiai/fiziológiai hatások

A sugar alcohol sweet tastant. Used in sweetness inhibition studies.

Jogi információk

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

PARTECK is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Biztonsági adatok

• Tárolási osztály kódja: 11 - Combustible Solids
• WGK: WGK 1