901572

Bromo-PEG₂-acid

≥95%

• Tapasztalati képlet (Hill-képlet): C₇H₁₃BrO₄
• CAS-szám: 1807503-92-9
• Molekulatömeg: 241.08
• MDL-szám: MFCD28122969
• UNSPSC kód: 12352101
• NACRES: NA.22

Tulajdonságok

• Teszt: ≥95%
• form: liquid
• reakcióalkalmasság: reagent type: linker
• funkcionális csoport: bromo; carboxylic acid
• tárolási hőmérséklet: −20°C
• SMILES string: BrCCOCCOCCC(O)=O

Leírás

Alkalmazás

Bromo-PEG₂-acid is a heterobifunctional, PEGylated crosslinker featuring a bromo group at one end and a carboxyl group at the other. The hydrophillic PEG linker facilitates solubility in biological applications. Bromo-PEG₂-acid can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC^® molecules) for targeted protein degradation.

This is a crosslinker with a bromo group on one end and a carboxyl group on the other end. The compound contains two PEG units to help improve solubility.

Jogi információk

PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license

Biztonsági adatok

• Tárolási osztály kódja: 10 - Combustible liquids
• WGK: WGK 3