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Interferon-α A Protein, Recombinant mouse

Interferon-α A Protein, Recombinant mouse.

Synonyme(s) :

Interferon alpha-2

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A propos de cet article

UNSPSC Code:
12352202
NACRES:
NA.75
eCl@ss:
32160405
Form:
liquid
Assay:
>95%
Biological source:
mouse
Recombinant:
expressed in E. coli
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biological source

mouse

Quality Level

recombinant

expressed in E. coli

assay

>95%

form

liquid

manufacturer/tradename

Chemicon®

technique(s)

cell culture | mammalian: suitable

UniProt accession no.

shipped in

dry ice

storage temp.

-65 to -96°C

General description

Product Source: Gene obtained from mouse DNA expressed in E. coli.
Purified Recombinant Mouse Interferon Alpha A (IFNalphaA)

Physical form

Frozen, in PBS containing 0.1% bovine serum albumin (BSA).

Preparation Note

After receipt, this product should be kept at -70°C or below for retention of full activity. When thawing, the contents of the tube should be apportioned in separate tubes so that freezing and thawing is kept to a minimum. Use polypropylene pipette tips and tubes when diluting this interferon. Dilute only in buffers containing protein such as 0.1% bovine serum albumin.

Analysis Note

Specific Activity: Determined by assaying inhibition of virus-induced cytopathic effect.In this antiviral assay for interferon, about 1 unit/mL of interferon is the quantity necessary to produce a cytopathic effect of 50%

Other Notes

Specific Activity: The units are determined with respect to the international reference standard for mouse interferon alpha (IFNalpha) provided by the National Institutes of Health.Unit of activity measured on mouse L929 cells with encephalomyocarditis virus (EMCV).

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Cet article
IF007IF005I9032
technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

biological source

mouse

biological source

human

biological source

mouse

biological source

mouse

assay

>95%

assay

95%

assay

>98% (SDS-PAGE and HPLC)

assay

≥95%

recombinant

expressed in E. coli

recombinant

expressed in E. coli

recombinant

-

recombinant

expressed in E. coli

form

liquid

form

liquid

form

liquid

form

buffered aqueous solution

UniProt accession no.

P01563, P01573

UniProt accession no.

P01563

UniProt accession no.

P01579, P01580

UniProt accession no.

P01575


Classe de stockage

12 - Non Combustible Liquids

wgk

WGK 2



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Tingting Deng et al.
Immunology and cell biology, 91(1), 52-59 (2012-09-19)
Toll-like receptor (TLR) activation by microbial pathogens triggers inflammatory responses against microbes. The phagocytic clearance of invading microbes and apoptotic immune cells is essential to resolve inflammation. However, the relationship between TLR activation and phagocytosis is poorly understood. We found
Jon B Suzich et al.
EMBO reports, 22(9), e52547-e52547 (2021-07-02)
Herpes simplex virus (HSV) establishes latent infection in long-lived neurons. During initial infection, neurons are exposed to multiple inflammatory cytokines but the effects of immune signaling on the nature of HSV latency are unknown. We show that initial infection of



Numéro d'article de commerce international

RéférenceGTIN
IF00904053252584077

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