Skip to Content
Merck
HomeServicesSoftware & Digital PlatformsCatalyst Screening with Catalexis

Catalyst Screening with Catalexis

Imagine simplifying complex cross-coupling reactions and minimizing trial and error in the lab. The Catalexis catalyst screening platform is a smart, data-driven solution that significantly enhances the efficiency of palladium-catalyzed cross-coupling reactions, such as the Buchwald-Hartwig Amination and Suzuki-Miyaura Coupling.

This hybrid solution offers chemists everything needed for successful catalyst optimization:

  • A curated set of 23 phosphine ligands, a palladium source, and access to the digital portal
  • Post-reaction data can be uploaded in the Catalexis portal for advanced algorithmic analysis, ranking the optimal phosphine ligands for your specific reaction

Catalexis not only streamlines material selection but also facilitates efficient scale-up strategies. Explore how Catalexis can integrate into your workflow, making catalysis research faster, more reliable, and scalable.

Request Information

User Testimonials

Discover how Catalexis is transforming labs – here’s what chemists are saying about their experience:

“Catalexis significantly streamlined our di-amination reaction optimization of 1,3-dichlorobenzene, saving time by providing a curated set of ligands to screen. After three rounds of screening, we identified the best ligand for our final industrial-scale process.”
Pharma Biotech Process Development Lab

“The suggested ligands delivered excellent results, including some I hadn’t initially considered trying.”
Academic Medicinal Chemistry Lab

"Catalexis is a nice tool wherein a kit of 23 ligands has the potential to evaluate and predict the performance of around 500 ligands with the help of AI."
Synthetic R&D Chemist

The Catalexis algorithm has been designed to work with a curated set of phosphine ligands that effectively represent the ligand chemical space. For a complete list of components in the standard kit, please fill out the contact form below. Ligands are also available for individual purchase.

Request More Information

Related Resources

Related Product Categories
Phosphine Ligands
Explore a wide array of phosphine ligands for cross-coupling reactions and diverse applications.
Cross-Coupling Catalysts
We offer an extensive portfolio of nickel and palladium catalysts to aid in the creation of C–C, C–N, and C–O bonds through common cross-coupling reactions.
Buchwald Catalysts & Ligands
Buchwald Catalysts and Ligands enable versatile cross-coupling reactions for C-C, C-N, and other bond formations.
Chiral Catalysts & Ligands
We are committed to providing unprecedented accessibility to chiral catalysts and ligands for a wide variety of C–H, C–C, C–N, and C–O bond-forming transformations.
Transition Metal Catalysts
Discover our unparalleled portfolio of transition metal catalysts for your different organic and organometallic chemistry-based applications.
Photoreactors
Photoreactors portfolio for optimized photoredox catalysis with various light sources, including parallel synthesis and photobiological reactions.
Related Applications
Lead Discovery
Lead discovery or lead identification for drug discovery utilizes screening methods, such as high throughput screening (HTS) or DNA Encoded Library (DEL) screening, to identify lead compounds.
Reaction Design & Optimization
Chemical reaction design and optimization in organic synthesis aims to precisely alter reaction parameters to achieve optimum results in finding pathways to target molecules.
Organic Reaction Toolbox
An organic reaction toolbox provides structure-activity relationships for unique chemical reactions to optimally design and control small molecule synthesis.
Fluorination
Fluorination is the introduction of fluorine to a compound via electrophilic fluorination, nucleophilic fluorination, difluoromethylation, trifluoromethylation, or perfluoroalkylation.
C–H Functionalization
C–H functionalization is the reliable and predictable conversion of a C–H into a C–C, C–N, C–O, or C–X bond in a selective and controlled fashion.
Photocatalysis
Photoredox catalysis uses visible light and photocatalysts for synthetic transformations like cross-coupling and functionalization reactions.
Related Services
SYNTHIA™ Retrosynthesis Software
Our custom cell culture product design experts can offer advice and support as you scale your bioprocess from clinical to commercial supply, assisting with liquid products, dry powder products, selection of raw materials, quality testing, flexible product packaging, and product documentation.
AIDDISON™ AI Drug Discovery
AIDDISON™ software supports drug discovery through molecular design, pharmacophore searches, and molecular docking for effective screening.
Small Molecule Library Design
Aldrich Market Select offers online ordering of small molecule libraries and chemistry building blocks for compound management.
Software & Digital Platforms
Explore LANEXO® and Synthia™ software solutions for lab inventory, safety, compliance, and synthetic pathway analysis.
Related Products
Loading
Sign In To Continue

To continue reading please sign in or create an account.

Don't Have An Account?