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Fortfahren mit
A4665
Alamethicin aus Trichoderma viride
≥98% (HPLC)
Synonym(e):
Antibiotikum U-22324
Größe auswählen
| Ihnen/SKU | Verfügbarkeit | Preis |
|---|---|---|
5 mg | Warenkorb auf Verfügbarkeit prüfen | € 299,00 |
10 mg | Warenkorb auf Verfügbarkeit prüfen | € 502,00 |
25 mg | Warenkorb auf Verfügbarkeit prüfen | € 1.000,00 |
Über diesen Artikel
Quality Segment
assay
≥98% (HPLC)
form
powder
antibiotic activity spectrum
Gram-positive bacteria
mode of action
cell membrane | interferes
storage temp.
2-8°C
SMILES string
CC(C)C[C@H](NC(=O)CNC(=O)C(C)(C)NC(=O)[C@@H](NC(=O)C(C)(C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)C(C)(C)NC(=O)[C@H](C)NC(=O)C(C)(C)NC(=O)[C@@H]1CCCN1C(=O)C(C)(C)NC(C)=O)C(C)C)C(=O)NC(C)(C)C(=O)N2CCC[C@H]2C(=O)N[C@@H](C(C)C)C(=O)NC(C)(C)C(=O)NC(C)(C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CO)Cc3ccccc3
InChI
1S/C92H150N22O25/c1-47(2)43-58(72(127)108-92(24,25)84(139)113-41-29-33-59(113)73(128)103-65(48(3)4)75(130)111-90(20,21)82(137)112-89(18,19)80(135)102-56(37-40-64(120)121)70(125)101-55(35-38-61(93)117)69(124)98-54(46-115)44-53-31-27-26-28-32-53)99-63(119)45-95-77(132)85(10,11)110-76(131)66(49(5)6)104-81(136)88(16,17)107-71(126)57(36-39-62(94)118)100-67(122)50(7)96-78(133)86(12,13)106-68(123)51(8)97-79(134)87(14,15)109-74(129)60-34-30-42-114(60)83(138)91(22,23)105-52(9)116/h26-28,31-32,47-51,54-60,65-66,115H,29-30,33-46H2,1-25H3,(H2,93,117)(H2,94,118)(H,95,132)(H,96,133)(H,97,134)(H,98,124)(H,99,119)(H,100,122)(H,101,125)(H,102,135)(H,103,128)(H,104,136)(H,105,116)(H,106,123)(H,107,126)(H,108,127)(H,109,129)(H,110,131)(H,111,130)(H,112,137)(H,120,121)/t50-,51-,54+,55-,56-,57-,58-,59-,60-,65-,66-/m0/s1
InChI key
LGHSQOCGTJHDIL-SLKIUSOBSA-N
General description
Application
- zur Untersuchung der Wirkung der Glutamattransporter auf das Na+/K+-ATPase-abhängige extrazelluläre K+, das während der neuronalen Aktivität transient ist[3]
- zur Untersuchung der Bildung von Anionen-permeablen Kanälen in planaren Lipiddoppelschichten durch Magainin I, gewonnen aus der Haut von Xenopus[1]
- zur Untersuchung der Permeabilität des apikalen Meristems und der Epidermis von Wurzeln und zellulaseinduzierter Resistenz gegenüber Alamethicin bei Arabidopsis thaliana[2]
- zur Untersuchung der zytotoxischen Wirkungen der Okadasäure von Algentoxinen und Mykotoxinen auf die menschlichen Darm-(HT-29) und Neuroblastom(SH-SY5Y)-Zelllinien[4]
- zur Analyse der strukturellen Variationen und biologischen Aktivität von aus der Longibrachiatum-Klade der Gattung der filamentösen Pilze Trichoderma gewonnenen Peptaibolen.[5]
Biochem/physiol Actions
Analysis Note
Other Notes
1 of 1
Dieser Artikel | |||
|---|---|---|---|
| antibiotic activity spectrum Gram-positive bacteria | antibiotic activity spectrum Gram-positive bacteria | antibiotic activity spectrum fungi, yeast | antibiotic activity spectrum fungi, yeast |
| mode of action cell membrane | interferes | mode of action cell membrane | interferes | mode of action cell membrane | interferes | mode of action cell membrane | interferes |
| Quality Level 300 | Quality Level 200 | Quality Level 300 | Quality Level 300 |
| assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ~80% (HPLC) | assay ~80% (HPLC) |
| form powder | form DMSO solution | form powder | form solid |
| storage temp. 2-8°C | storage temp. −20°C | storage temp. 2-8°C | storage temp. 2-8°C |
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral
Lagerklasse
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
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How is shipping temperature determined? And how is it related to the product storage temperature?
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Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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