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GABRA2

gamma-aminobutyric acid (GABA) A receptor, alpha 2

Synonyme:
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(2555) Summary: GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(14395) gamma-aminobutyric acid (GABA) A receptor, subunit alpha 2
  • Rat(289606) gamma-aminobutyric acid (GABA) A receptor, alpha 2
  • cow(282236) gamma-aminobutyric acid (GABA) A receptor, alpha 2
  • chicken(770511) gamma-aminobutyric acid (GABA) A receptor, alpha 2
  • naked mole-rat(101720776) gamma-aminobutyric acid (GABA) A receptor, alpha 2
  • domestic guinea pig(100720796) gamma-aminobutyric acid (GABA) A receptor, alpha 2
  • domestic cat(100286789) gamma-aminobutyric acid (GABA) A receptor, alpha 2
  • Domestic Rabbit(100339376) gamma-aminobutyric acid (GABA) A receptor, alpha 2
  • sheep(101121265) gamma-aminobutyric acid (GABA) A receptor, alpha 2
  • Horse(100061914) gamma-aminobutyric acid (GABA) A receptor, alpha 2
  • dog(482131) gamma-aminobutyric acid (GABA) A receptor, alpha 2

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Small Molecule - Agonist

Produktnummer
Beschreibung
Spezies
(±)-Baclofen, ≥98% (HPLC), solid,
Spezies
human, rat
Gaboxadol -hydrochlorid, solid, ≥98% (HPLC),
Spezies
human
Muscimol hydrobromide, ≥98% (HPLC), solid,
Spezies
human
Isoguvacine hydrochloride, solid,
Spezies
human
Piperidine-4-sulfonic acid, ,
Spezies
human

Small Molecule - Allosteric Modulator

Produktnummer
Beschreibung
Spezies
5β-Pregnan-3α-ol-20-one, ,
Spezies
Dehydroisoandrosteron-3-Sulfat Natriumsalz Dihydrat, ≥93% (TLC), powder,
Spezies
human
3α,21-Dihydroxy-5α-pregnan-20-one, ≥95%,
Spezies
human
trans-Dehydroandrosteron, ≥99%,
Spezies
human, rat
Etomidat, >98% (HPLC), powder,
Spezies
human

Small Molecule - Antagonist

Produktnummer
Beschreibung
Spezies
2-Pyrrolidinon, ≥99%,
Spezies
2-Pyrrolidinon, 99%,
Spezies
Muscimol, powder,
Spezies
β-Naphthoflavon, ≥98%,
Spezies
(+)-Bicucullin, ≥97.0% (TLC),
Spezies

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-GABA(A) Receptor α2 Antibody, clone N399/19, clone N399/19, from mouse,
Speziesreaktivität
human, mouse, rat
Anwendung
immunohistochemistry
western blot
Anti-GABRA2 antibody produced in rabbit, IgG fraction of antiserum,
Speziesreaktivität
bovine, dog, horse, human, mouse, rabbit, rat
Anwendung
western blot
Monoclonal Anti-GABA A Receptor antibody produced in mouse, clone S399-19,
Speziesreaktivität
human, rat
Anwendung
immunofluorescence
western blot
Monoclonal Anti-GABA A Receptor-Allophycocyanin antibody produced in mouse, clone S399-19,
Speziesreaktivität
human, rat
Anwendung
immunofluorescence
western blot
Monoclonal Anti-GABA A Receptor-Biotin antibody produced in mouse, clone S399-19,
Speziesreaktivität
human, rat
Anwendung
immunofluorescence
western blot

Small Molecule - Inhibitor

Produktnummer
Beschreibung
Spezies
Norharman, crystalline,
Spezies
human
Harman, 98%,
Spezies
human
Flavon, ≥99.0%,
Spezies
human, rat, mouse
Chrysin, ≥96.5%,
Spezies
human, mouse
NO-711 hydrochloride, ≥98% (HPLC),
Spezies
human

Small Molecule - Ligand

Produktnummer
Beschreibung
Spezies
Etomidat, >98% (HPLC), powder,
Spezies
human
Flumazenil, >99% (HPLC), solid,
Spezies
rat, human
Carbamazepin, powder,
Spezies
rat, human
2-Brom-2-chlor-1,1,1-trifluorethan, ≥99%,
Spezies
human

Small Molecule - Mixed Agonist/Antagonist

Produktnummer
Beschreibung
Spezies
Etiocholan-3α-ol-17-on, ,
Spezies
human, rat
Ganaxolone, ≥98% (HPLC), solid,
Spezies
human, mouse
5α-Pregnan-3α-ol-20-one, solid,
Spezies
human, mouse, rat

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting mouse Gabra2,
Spezies
mouse
MISSION® esiRNA, targeting human GABRA2,
Spezies
human