D5297

Dehydroisoandrosteron-3-Sulfat Natriumsalz Dihydrat

≥93% (TLC), GABAA modulator, powder

• Synonym(e): 5-Androsten-3β-ol-17-one sulfat Natriumsalz Dihydrat, Natrium-dehydroepiandrosteron-sulfat, Prasteron-sulfat Natriumsalz Dihydrat
• Empirische Formel (Hill-System): C₁₉H₂₇NaO₅S · 2H₂O
• CAS-Nummer: 78590-17-7
• Molekulargewicht: 426.50
• NACRES: NA.77
• PubChem Substance ID: 24278373
• UNSPSC Code: 12352200
• EC Number: 214-152-2
• MDL number: MFCD11045975
• Assay: ≥93% (TLC)
• Form: powder

Eigenschaften

• Produktname: Dehydroisoandrosteron-3-Sulfat Natriumsalz Dihydrat, ≥93% (TLC), powder
• Quality Segment: 200
• assay: ≥93% (TLC)
• form: powder
• drug control: Home Office Schedule 4.2; regulated under CDSA - not available from Sigma-Aldrich Canada
• color: white to off-white
• mp: 148-149 °C (dec.) (lit.)
• solubility: methanol: soluble, clear to hazy
• SMILES string: O.O.[Na+].C[C@]12CC[C@H]3[C@@H](CC=C4C[C@H](CC[C@]34C)OS([O-])(=O)=O)[C@@H]1CCC2=O
• InChI: 1S/C19H28O5S.Na.2H2O/c1-18-9-7-13(24-25(21,22)23)11-12(18)3-4-14-15-5-6-17(20)19(15,2)10-8-16(14)18;;;/h3,13-16H,4-11H2,1-2H3,(H,21,22,23);;2*1H2/q;+1;;/p-1/t13-,14-,15-,16-,18-,19-;;;/m0.../s1
• InChI key: NLNMKDUYGPNWAO-OXNWJOIVSA-M
• Gene Information: human ... GABRA1(2554), GABRA2(2555), GABRA3(2556), GABRA4(2557), GABRA5(2558), GABRA6(2559), GABRB1(2560), GABRB2(2561), GABRB3(2562)

Beschreibung

Application

Dehydroisoandrosterone 3-sulfate sodium salt dihydrate has been used as a supplement to induce superoxide anion production in human neutrophil granulocytes.

Biochem/physiol Actions

Dehydroisoandrosterone 3-sulfate sodium salt dihydrate is a negative allosteric modulator of GABA_A receptors.

Features and Benefits

This compound is a featured product for ADME Tox and Neuroscience research. Discover more featured ADME Tox and Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the GABAA Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)