GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
Synonimy:
ECA4, EJM, EJM5
Gatunek:
Human GABRA1 (2554), Mouse Gabra1 (14394), Rat Gabra1 (29705), domestic guinea pig Gabra1 (100721626), cow GABRA1 (780973), dog GABRA1 (489143), naked mole-rat Gabra1 (101719179), Zebrafish gabra1 (768183), sheep GABRA1 (101117759), chicken GABRA1 (374214)
Identyfikator UniProtKB:
Identyfikator genu:
- Human(2554) Summary: This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4. Multiple transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]
- Mouse(14394) gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1
- Rat(29705) gamma-aminobutyric acid (GABA) A receptor, alpha 1
- domestic guinea pig(100721626) gamma-aminobutyric acid (GABA) A receptor, alpha 1
- cow(780973) gamma-aminobutyric acid (GABA) A receptor, alpha 1
- dog(489143) gamma-aminobutyric acid (GABA) A receptor, alpha 1
- naked mole-rat(101719179) gamma-aminobutyric acid (GABA) A receptor, alpha 1
- Zebrafish(768183) gamma-aminobutyric acid (GABA) A receptor, alpha 1
- sheep(101117759) gamma-aminobutyric acid (GABA) A receptor, alpha 1
- chicken(374214) gamma-aminobutyric acid (GABA) A receptor, alpha 1
- domestic cat(100286792) gamma-aminobutyric acid (GABA) A receptor, alpha 1
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Small Molecule - Agonist
Numer produktu
Opis
Gatunek
Meprobamate solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Gatunek
human
Small Molecule - Allosteric Modulator
Numer produktu
Opis
Gatunek
Zolpidem solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Gatunek
human
Zaleplon solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Gatunek
human
Zolpidem for system suitability, CRS, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
Small Molecule - Antagonist
Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-GABA antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reaktywność gatunkowa
drosophila, rat, wide range
Zastosowanie
dot blot
immunohistochemistry
immunohistochemistry
Anti-GABA (No Gluteraldehyde) Antibody, Chemicon®, from rabbit,
Reaktywność gatunkowa
rat
Zastosowanie
immunohistochemistry
Anti-GABA A Receptor α1 chain Antibody, NT, clone BD24, clone BD24, Chemicon®, from mouse,
Reaktywność gatunkowa
avian, bovine, human, pig
Zastosowanie
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Przeciwciało przeciwko receptorowi GABA A β2/3, clone 62-3G1, Upstate®, from mouse,
Reaktywność gatunkowa
bovine, human, rat
Zastosowanie
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-GABRA1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
western blot
Small Molecule - Inhibitor
Small Molecule - Ligand
Small Molecule - Mixed Agonist/Antagonist
Numer produktu
Opis
Gatunek
Phenol, puriss., meets analytical specification of Ph. Eur., BP, USP, 99.5-100.5% (GC),
Gatunek
human