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A5751

Acetylthiocholine iodide

≥98% (TLC), powder or crystals

Sinónimos:

(2-Mercaptoethyl)trimethylammonium iodide acetate

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Fórmula lineal:
CH3COSCH2CH2N(CH3)3I
Número CAS:
Peso molecular:
289.18
UNSPSC Code:
12352204
NACRES:
NA.83
PubChem Substance ID:
EC Number:
217-474-1
Beilstein/REAXYS Number:
3916578
MDL number:
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Quality Level

assay

≥98% (TLC)

form

powder or crystals

color

white

mp

205-210 °C (lit.)

solubility

H2O: 100 mg/mL

storage temp.

2-8°C

SMILES string

[I-].CC(=O)SCC[N+](C)(C)C

InChI

1S/C7H16NOS.HI/c1-7(9)10-6-5-8(2,3)4;/h5-6H2,1-4H3;1H/q+1;/p-1

InChI key

NTBLZMAMTZXLBP-UHFFFAOYSA-M

General description

Acetylcholinesterase substrate and nicotinic acetylcholine receptor agonist.

Application

Substrate for the colorimetric determination of acetylcholinesterase activity.
Acetylthiocholine iodide has been used as a substrate in the preparation of acetylcholine esterase (AChE) assay working solution for AChE activity assay. It has also been used as a component in phosphate buffer (PB) for cholinesterase assay.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

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Este artículo
A56262082026978
assay

≥98% (TLC)

assay

≥99% (TLC)

assay

≥99.0% (AT)

assay

≥99.0% (AT)

solubility

H2O: 100 mg/mL

solubility

water: 100 mg/mL, clear to slightly hazy, colorless

solubility

-

solubility

H2O: 1 M, clear, colorless

Quality Level

100

Quality Level

200

Quality Level

300

Quality Level

200

form

powder or crystals

form

powder

form

crystalline

form

powder or crystals

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

-

color

white

color

-

color

-

color

colorless to white


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Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Oral

Clase de almacenamiento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges



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Perez GR, et al.
The Journal of Biological Chemistry, 287(51), 43108-43115 (2012)
Anti-acetylcholinesterase activities of traditional Chinese medicine for treating Alzheimer's disease
Lin HQ, et al.
Chemico-Biological Interactions, 175(1-3), 352-354 (2008)



Número de artículo de comercio global

SKUGTIN
A5751-25G04061833376294
A5751-1G04061835553501
A5751-5G04061835553518
A5751-250MG04061833376287

Questions

  1. Is the powder form of Acetylthiocholine iodide suitable for Ellman's assay or do you have to prepare it into a solution? If so, do you have any guide on how to prepare it into a solution?

    1 answer
    1. This product has not been tested for suitability in the Ellman's Assay, however it has been cited in the publication below. In addition, see product D8130, DTNB Ellman's reagent.
      Cholinesterase assay by an efficient fixed time endpoint method
      https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4473035/

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