UC431

4-Hydroxymidazolam

≥97% (HPLC), solid

• Synonym(s): 8-Chloro-6-(2-fluorophenyl)-4-hydroxy-4H-imidazo[1,5a][1,4]bezodiazepine
• Empirical Formula (Hill Notation): C₁₈H₁₃ClFN₃O
• CAS Number: 59468-85-8
• Molecular Weight: 341.77
• UNSPSC Code: 12161501
• PubChem Substance ID: 24724656
• NACRES: NA.77
• MDL number: MFCD00871459
• Form: solid

Properties

• Product Name: 4-Hydroxymidazolam,
• form: solid
• drug control: regulated under CDSA - not available from Sigma-Aldrich Canada
• color: white to off-white
• mp: 186-187 °C
• storage temp.: 2-8°C
• SMILES string: FC(C=CC=C1)=C1C2=NC(O)C3=CN=C(C)N3C4=C2C=C(Cl)C=C4
• InChI: 1S/C18H13ClFN3O/c1-10-21-9-16-18(24)22-17(12-4-2-3-5-14(12)20)13-8-11(19)6-7-15(13)23(10)16/h2-9,18,24H,1H3
• InChI key: ZYISITHKPKHPKG-UHFFFAOYSA-N

Description

Application

4′-Hydroxymidazolam can be used in cell biology studies. It can also be used for studying cell signaling and neuroscience.

Biochem/physiol Actions

4′-Hydroxymidazolam is the minor hydroxylated metabolite of Midazolam (MDZ). The product contributes in the pharmacological impact of MDZ.[1]

CYP3A4 metabolite of midazolam.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Safety Information

• pictograms: GHS06
• signalword: Danger
• hcodes: H301
• pcodes: P264 - P270 - P301 + P310 - P405 - P501
• Hazard Classifications: Acute Tox. 3 Oral
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)