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(S)-(+)-Nirvanol

Name: (S)-(+)-Nirvanol
Brand: SIGMA

Synonym(s):

(S)-(+)-5-Ethyl-5-phenyl-2,4-imidazolidinedione, (S)-(+)-5-Ethyl-5-phenylhydantoin

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About This Item

Empirical Formula (Hill Notation):

C₁₁H₁₂N₂O₂

CAS Number:

65567-34-2

Molecular Weight:

204.23

NACRES:

NA.77

PubChem Substance ID:

329827656

UNSPSC Code:

12161501

MDL number:

MFCD00272652

Form:

solid

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Properties

form

solid

Quality Segment

200

color

off-white

solubility

DMF: soluble

storage temp.

2-8°C

SMILES string

CC[C@]1(NC(=O)NC1=O)c2ccccc2

InChI

1S/C11H12N2O2/c1-2-11(8-6-4-3-5-7-8)9(14)12-10(15)13-11/h3-7H,2H2,1H3,(H2,12,13,14,15)/t11-/m0/s1

InChI key

UDTWZFJEMMUFLC-NSHDSACASA-N

Description

Biochem/physiol Actions

5-ethyl-5-phenylhydantoin (EPH) is a long-acting sedative. It is implicated to favor hepatocellular and thyroid follicular cell tumor progression.[1]

CYP2B6 metabolite of (R)-(-)-mephenytoin; anticonvulsant; hypnotic.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Preparation Note

Nirvanol is soluble in DMF.

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1 of 1

This Item	UC179	B8686	UC175
Sigma-Aldrich UC180 (S)-(+)-Nirvanol	Sigma-Aldrich UC179 (R)-(−)-Nirvanol	Sigma-Aldrich B8686 (+)-N-3-Benzylnirvanol	Sigma-Aldrich UC175 (S)-(+)-Mephenytoin
form solid	form solid	form powder	form solid
Quality Level 200	Quality Level 200	Quality Level 100	Quality Level 200
storage temp. 2-8°C	storage temp. 2-8°C	storage temp. 2-8°C	storage temp. 2-8°C
solubility DMF: soluble	solubility DMF: soluble	solubility DMSO: >20 mg/mL, H₂O: insoluble	solubility DMSO: soluble
color off-white	color off-white	color -	color off-white

pictograms

GHS07

signalword

Warning

hcodes

H302,H315,H319,H335

pcodes

P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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