T1016
Trichlormethiazide
≥98%
Synonym(s):
6-Chloro-3-(dichloromethyl)-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
(+/-)-, NSC 61560
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About This Item
Empirical Formula (Hill Notation):
C8H8Cl3N3O4S2
CAS Number:
Molecular Weight:
380.66
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
205-118-8
MDL number:
Pricing and availability is not currently available.
Quality Level
assay
≥98%
SMILES string
NS(=O)(=O)c1cc2c(NC(NS2(=O)=O)C(Cl)Cl)cc1Cl
InChI
1S/C8H8Cl3N3O4S2/c9-3-1-4-6(2-5(3)19(12,15)16)20(17,18)14-8(13-4)7(10)11/h1-2,7-8,13-14H,(H2,12,15,16)
InChI key
LMJSLTNSBFUCMU-UHFFFAOYSA-N
Gene Information
human ... SLC12A3(6559)
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signalword
Danger
hcodes
Hazard Classifications
Resp. Sens. 1 - Skin Sens. 1
Storage Class
13 - Non Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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I Kuwajima et al.
Hypertension research : official journal of the Japanese Society of Hypertension, 24(5), 475-480 (2001-10-26)
A randomized prospective controlled study, the National Interventional Cooperative Study in Elderly Hypertensives (NICS-EH), previously demonstrated that the preventive effect of the long-acting calcium channel blocker nicardipine on the cardiovascular endpoint was similar to that of the diuretic, trichlormethiazide. The
Susumu Ogawa et al.
Hypertension (Dallas, Tex. : 1979), 47(4), 699-705 (2006-03-01)
We tested the hypothesis that blockade of angiotensin II type 1 receptors reduces oxidative stress markers in parallel with urinary albumin and type IV collagen excretions. Sixty-six diabetic patients with nephropathy were randomly assigned to either the angiotensin II receptor
Salt-losing nephrogenic diabetes insipidus caused by fetal exposure to angiotensin receptor blocker.
Kenichiro Miura et al.
Pediatric nephrology (Berlin, Germany), 24(6), 1235-1238 (2009-01-21)
The administration of angiotensin-converting enzyme inhibitors (ACEIs) or angiotensin type 1 receptor blockers (ARBs) to pregnant women has been reported to cause ACEI/ARB fetopathy, including oligohydramios, pulmonary hypoplasia, renal insufficiency, limb contracture, and fetal hypotension in the child. Most of
Global Trade Item Number
| SKU | GTIN |
|---|---|
| T1016-5G | 04061837336379 |
| T1016-1G | 04061837336331 |