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Pamoic acid disodium salt

Name: Pamoic acid disodium salt
Brand: SIGMA

Synonym(s):

4,4′-Methylenebis(3-hydroxy-2-naphthoic acid), Embonic acid, Sodium pamoate

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About This Item

Linear Formula:

C₂₃H₁₄O₆Na₂

CAS Number:

6640-22-8

Molecular Weight:

432.33

NACRES:

NA.25

PubChem Substance ID:

24898580

UNSPSC Code:

12352106

EC Number:

229-653-1

MDL number:

MFCD00036183

Form:

powder

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Properties

form

powder

Quality Level

100

SMILES string

[Na].OC(=O)c1cc2ccccc2c(Cc3c(O)c(cc4ccccc34)C(O)=O)c1O

InChI

1S/C23H16O6.Na.H/c24-20-16(14-7-3-1-5-12(14)9-18(20)22(26)27)11-17-15-8-4-2-6-13(15)10-19(21(17)25)23(28)29;;/h1-10,24-25H,11H2,(H,26,27)(H,28,29);;

InChI key

ZRZSXMUASGHHKP-UHFFFAOYSA-N

Description

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This Item	45150	16682	1493000
Sigma-Aldrich P5022 Pamoic acid disodium salt	Sigma-Aldrich 45150 Pamoic acid	Sigma-Aldrich 16682 (R)-Pantoic acid sodium salt	USP 1493000 Pamoic acid
form powder	form -	form -	form -
Quality Level 100	Quality Level 100	Quality Level 100	Quality Level -

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Synchronized Ratiometric Codelivery of Metformin and Topotecan through Engineered Nanocarrier Facilitates In Vivo Synergistic Precision Levels at Tumor Site.

Venkatesh Teja Banala et al.

Advanced healthcare materials, 7(19), e1800300-e1800300 (2018-08-14)

The combination of metabolic modulators with chemotherapy holds vast promise for effective inhibition of tumor progression and invasion. Herein, a ratiometric codelivery platform is developed for metformin (MET), a known metabolic modulator and topotecan (TPT), a chemotherapeutic drug, by engineering

Development and evaluation of a 68Ga labeled pamoic acid derivative for in vivo visualization of necrosis using positron emission tomography.

Kristof Prinsen et al.

Bioorganic & medicinal chemistry, 18(14), 5274-5281 (2010-06-29)

In this study, we labeled N,N'-bis(diethylenetriamine pentaacetic acid)-pamoic acid bis-hydrazide (bis-DTPA-PA) with the generator produced PET radionuclide gallium-68 and evaluated 68Ga-bis-DTPA-PA as a potential tracer for in vivo visualization of necrosis by positron emission tomography (PET). Radiolabeling was achieved with

Necrosis avidity of (99m)Tc(CO)3-labeled pamoic acid derivatives: synthesis and preliminary biological evaluation in animal models of necrosis.

Humphrey Fonge et al.

Bioconjugate chemistry, 18(6), 1924-1934 (2007-10-13)

In a search for an infarct avid tracer agent with improved properties, we have observed that bis-DTPA derivatives of pamoic acid have a high avidity for necrotic tissue. Here, we report the synthesis, radiolabeling, and preliminary evaluation in normal mice

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Global Trade Item Number

SKU	GTIN
P5022-25G	04061835327003

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