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M5757

Sigma-Aldrich

Maleic acid sodium salt

~99%

Synonym(s):

cis-Butenedioic acid, Toxilic acid

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About This Item

Linear Formula:
C4H3O4Na
CAS Number:
3105-55-3
Molecular Weight:
138.05
EC Number:
221-461-6
MDL number:
MFCD00070246
UNSPSC Code:
12352106
PubChem Substance ID:
24897040
NACRES:
NA.77

Assay

~99%

SMILES string

OC(/C=C\C([O-])=O)=O.[Na+]

InChI

1S/C4H4O4.Na/c5-3(6)1-2-4(7)8;/h1-2H,(H,5,6)(H,7,8);/q;+1/p-1/b2-1-;

InChI key

VRVKOZSIJXBAJG-ODZAUARKSA-M

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Biochem/physiol Actions

Maleic acid is a component of cosmetics, fragrances and has industrial applications. It is also a potent nephrotoxin and is implicated to induce glycosuria, aminoaciduria and Fanconi syndrome.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Mei-Ling Hou et al.
Molecules (Basel, Switzerland), 21(3), 367-367 (2016-03-22)
Maleic acid has been shown to be used as a food adulterant in the production of modified starch by the Taiwan Food and Drug Administration. Due to the potential toxicity of maleic acid to the kidneys, this study aimed to
Carmen María Ferrer-Luque et al.
Journal of endodontics, 38(6), 826-828 (2012-05-19)
The use of chelating agents in endodontic treatment is required to remove the smear layer and to achieve better disinfection within the root canal system. The aim of this study was to evaluate the residual antimicrobial activity of 17% ethylenediaminetetraacetic
Shirley A Aguirre et al.
Toxicologic pathology, 40(5), 797-806 (2012-05-04)
Maleic acid was formulated in 0.7% saline and injected intravitreally in rabbits in order to evaluate ocular safety and tolerability. Maleic acid was formulated within a narrow pH range (2-3), administered in a fixed volume (100 µl), and concentrations ranged
Nidambur Vasudev Ballal et al.
Journal of endodontics, 37(10), 1402-1405 (2011-09-20)
The elimination of microorganisms from the root canal system necessitates the use of combination of irrigating solutions to enhance their antimicrobial property. The combination of irrigants and their interaction sometimes could be detrimental to the outcome of the root canal
Pierangelo Gobbo et al.
Langmuir : the ACS journal of surfaces and colloids, 28(33), 12357-12363 (2012-08-14)
Improved methodology to prepare maleimide-functionalized, water-soluble, small (<3 nm) gold nanoparticles using a retro-Diels-Alder strategy that we developed for similar organic-soluble AuNP's is described. Importantly, our results suggest that a recent paper by Zhu, Waengler, Lennox, and Schirrmacher describing a
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