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M4199

Myelin Oligodendrocyte Glycoprotein (40-54), Rat, Mouse

lyophilized powder

Synonym(s):

MOG (40-54)

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About This Item

Empirical Formula (Hill Notation):
C84H127N27O21
CAS Number:
Molecular Weight:
1851.08
NACRES:
NA.32
UNSPSC Code:
12352202
Form:
lyophilized powder
Assay:
≥97% (HPLC)
Biological source:
rat
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biological source

rat

Quality Level

assay

≥97% (HPLC)

form

lyophilized powder

color

white

solubility

deionized water: soluble

UniProt accession no.

storage temp.

−20°C

Gene Information

mouse ... Mog(17441)
rat ... Mog(24558)

Biochem/physiol Actions

The 21-residue peptide MOG 35-55 contains an antigenic epitope responsible for the activation of CD8 encephalitogenic T cells in mice. Two truncated peptides, MOG 40-54 and MOG 44-54 were shown to bind the recombinant H-2Db protein. This complex then binds MOG specific CD8 T cells. While MOG 40-54 retained the full capability of inducing paralytic disease, MOG 44-54 only partialy causes clinical paralysis and central nervous system inflamation.

Physical form

Lyophilized from 0.1% aqueous TFA.

Other Notes

Lyophilized from 0.1% TFA in H2O

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This Item
M4324M4939M5063
biological source

rat

biological source

-

biological source

-

biological source

rat

assay

≥97% (HPLC)

assay

-

assay

≥97% (HPLC)

assay

>95% (SDS-PAGE)

form

lyophilized powder

form

lyophilized powder

form

powder

form

lyophilized powder

UniProt accession no.

Q61885, Q63345

UniProt accession no.

Q61885, Q63345

UniProt accession no.

Q61885, Q63345

UniProt accession no.

P07722

solubility

deionized water: soluble

solubility

deionized water: soluble

solubility

-

solubility

-

Gene Information

mouse ... Mog(17441)
rat ... Mog(24558)

Gene Information

mouse ... Mog(17441)
rat ... Mog(24558)

Gene Information

mouse ... Mog(17441)
rat ... Mog(24558)

Gene Information

rat ... Mag(29409)


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Novel pathogenic epitopes of myelin oligodendrocyte glycoprotein induce experimental autoimmune encephalomyelitis in C57BL/6 mice
Cecile Delarasse
Immunology (2013)
Oligodendrocyte myelin glycoprotein (OMgp) in rat hippocampus is depleted by chronic ethanol consumption.
Okamoto H
Neuroscience Letters (2006)



Global Trade Item Number

SKUGTIN
M4199-500UG04061833266021
M4199-1MG04061826703496

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