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M1574

Miglitol

Synonym(s):

1-(2-Hydroxyethyl)-2-(hydroxymethyl)piperidine-3,4,5-triol

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About This Item

Empirical Formula (Hill Notation):
C8H17NO5
CAS Number:
72432-03-2
Molecular Weight:
207.22
UNSPSC Code:
12352205
EC Number:
276-661-6
NACRES:
NA.25
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biological source

synthetic (organic)

Quality Level

200

assay

≥98% (HPLC)

form

powder

mp

142-147  °C

solubility

water: 5 mg/mL, clear, colorless to faintly yellow

storage temp.

room temp

SMILES string

N1([C@@H]([C@H]([C@@H]([C@H](C1)O)O)O)CO)CCO

InChI

1S/C8H17NO5/c10-2-1-9-3-6(12)8(14)7(13)5(9)4-11/h5-8,10-14H,1-4H2/t5-,6+,7-,8-/m1/s1

InChI key

IBAQFPQHRJAVAV-ULAWRXDQSA-N

General description

Miglitol is an alpha-glucosidase inhibitor used as a glucose-lowering drug in diabetes research.[1]

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This Item
B6032B753514879
Miglitol

Sigma-Aldrich

M1574

Miglitol

BIS-TRIS hydrochloride ≥99.0% (titration)

Sigma-Aldrich

B6032

BIS-TRIS hydrochloride

BIS-TRIS BioXtra, ≥98.0% (titration)

Sigma-Aldrich

B7535

BIS-TRIS

BIS-TRIS BioUltra, ≥99.0% (NT)

Sigma-Aldrich

14879

BIS-TRIS

biological source

synthetic (organic)

biological source

-

biological source

-

biological source

-

assay

≥98% (HPLC)

assay

≥99.0% (titration)

assay

≥98.0% (titration)

assay

≥99.0% (NT)

Quality Level

200

Quality Level

200

Quality Level

400

Quality Level

200

form

powder

form

crystalline powder

form

powder

form

powder

solubility

water: 5 mg/mL, clear, colorless to faintly yellow

solubility

water: 0.5 g/mL, clear, colorless to very faintly yellow

solubility

H2O: 1 M, clear, colorless

solubility

H2O: 1 M at 20 °C, clear, colorless

storage temp.

room temp

storage temp.

room temp

storage temp.

-

storage temp.

-

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
0000471235
0000467355
0000471235
0000467355
0000296611

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Kazuki Mochizuki et al.
Bioscience, biotechnology, and biochemistry, 74(12), 2470-2474 (2010-12-15)
β(2) integrins (CD11s/CD18) promote the attachment of leukocytes to vascular endothelial cells. We performed in this study sucrose loading to rats with moderate postprandial hyperglycemia with/without once-daily dosing of the α-glucosidase inhibitor, miglitol, for 4 days under 4-h fasting conditions.
Kazuki Mochizuki et al.
Metabolism: clinical and experimental, 60(11), 1560-1565 (2011-05-10)
Otsuka Long-Evans Tokushima Fatty (OLETF) rats, an animal model of type 2 diabetes mellitus, exhibit chronic and slowly progressive hyperglycemia with obesity. In this study, we examined whether dietary supplementation with the α-glucosidase inhibitor miglitol from the preonset stage improves
Kenichi Matsuura et al.
Diabetes technology & therapeutics, 14(5), 423-429 (2012-02-10)
We compared the effects of miglitol as an add-on to bolus insulin and dose-intensified bolus insulin on postprandial glycemic excursions by continuous glucose monitoring (CGM). The glucose levels of 21 type 2 diabetes patients admitted for glycemic control were monitored
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Global Trade Item Number

SKUGTIN
M1574-25MG04061834040934

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