M0317
Microsomes from Liver, Pooled
from human
Synonym(s):
Liver Microsomes
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About This Item
NACRES:
NA.47
UNSPSC Code:
12161501
Pricing and availability is not currently available.
Application
Microsomes from liver have been used to study the in vitro effect of Clinacanthus nutans leaves on the activity of cytochrome P450 3A4 and 2E1.
Biochem/physiol Actions
Liver microsomes are subcellular particles derived from the endoplasmic reticulum of hepatic cells. These microsomes are a rich source of drug metabolizing enzymes, including cytochrome P-450. Microsome pools from various sources are useful in the study of xenobiotic metabolism and drug interactions.
Source of drug metabolizing enzymes, including cytochrome P-450.
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| biological source human | biological source mouse (CD-1) | biological source mouse (CD-1) | biological source rat (Sprague-Dawley) |
| Quality Level 200 | Quality Level 200 | Quality Level 200 | Quality Level 200 |
| packaging vial of ~10 mg | packaging vial of ~10 mg | packaging vial of 1.0 mL | packaging vial of ~20 mg |
| storage temp. −70°C | storage temp. −70°C | storage temp. −70°C | storage temp. −70°C |
| shipped in dry ice | shipped in dry ice | shipped in dry ice | shipped in dry ice |
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Storage Class
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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