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C7628

Sigma-Aldrich

5β-Cholanic acid

≥99% (TLC)

Synonym(s):

Ursocholanic acid

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About This Item

Empirical Formula (Hill Notation):
C24H40O2
CAS Number:
546-18-9
Molecular Weight:
360.57
MDL number:
MFCD00065904
UNSPSC Code:
12352106
PubChem Substance ID:
24892974
NACRES:
NA.77

Quality Level

200

Assay

≥99% (TLC)

form

powder

SMILES string

[H]C12CCCCC1(C)C3CCC4(C)C(CCC4C3CC2)[C@@H](C)CCC(O)=O

InChI

1S/C24H40O2/c1-16(7-12-22(25)26)19-10-11-20-18-9-8-17-6-4-5-14-23(17,2)21(18)13-15-24(19,20)3/h16-21H,4-15H2,1-3H3,(H,25,26)

InChI key

RPKLZQLYODPWTM-UHFFFAOYSA-N

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Gregory P Tochtrop et al.
The Journal of organic chemistry, 67(19), 6764-6771 (2002-09-14)
Synthetic methodology that allows for incorporation of isotopic carbon at the C-3 and C-4 positions of bile salts is reported. Three [3,4-(13)C(2)]-enriched bile salts were synthesized from either deoxycholic or lithocholic acid. The steroid 3alpha-OH group was oxidized and the
Allan D Heibein et al.
BMC cancer, 12, 381-381 (2012-09-04)
Since proteins involved in chemotherapy drug pharmacokinetics and pharmacodynamics have a strong impact on the uptake, metabolism, and efflux of such drugs, they likely play critical roles in resistance to chemotherapy drugs in cancer patients. To investigate this hypothesis, we
Jae Hyung Park et al.
Journal of controlled release : official journal of the Controlled Release Society, 95(3), 579-588 (2004-03-17)
The synthetic peptide bearing Arg-Gly-Asp (RGD) sequence is considered to specifically bind to alpha(v)beta(3) integrin expressed on endothelial cells in the angiogenic blood vessels, which provides a potential to inhibit the tumor growth. As a carrier for the RGD peptide
Emilio Bottari et al.
Annali di chimica, 95(7-8), 479-490 (2005-10-21)
To study the composition of sodium cholate solutions, an investigation was carried out at 25 degrees C and in N(CH3)4Cl, as a constant ionic medium, at three different concentrations (W = 0.100; 0.500 and 0.800 mol dm(-3)). Electromotive force measurements
Jin Hee Na et al.
Journal of controlled release : official journal of the Controlled Release Society, 163(1), 2-9 (2012-08-01)
To evaluate the tumor targeting efficiency of self-assembled polymeric nanoparticles, four glycol chitosan nanoparticles (CNPs) with different degrees of hydrophobic substitution were prepared by coupling 7.5, 12, 23, and 35 wt.% of 5β-cholanic acid to hydrophilic glycol chitosan polymer (GC).
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