Z-Gly-Pro-Arg p-nitroanilide acetate salt

Name: Z-Gly-Pro-Arg p-nitroanilide acetate salt
Brand: SIGMA

protease substrate

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About This Item

Empirical Formula (Hill Notation):

C₂₇H₃₄N₈O₇ · xC₂H₄O₂

CAS Number:

66648-35-9

Molecular Weight:

582.61 (free base basis)

NACRES:

NA.32

PubChem Substance ID:

329774987

UNSPSC Code:

12352204

MDL number:

MFCD18782526

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Properties

Quality Segment

200

assay

≥98% (TLC)

form

powder

solubility

methanol: 20 mg/mL, clear, colorless to light yellow

storage temp.

−20°C

SMILES string

CC(O)=O.NC(=N)NCCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)OCc2ccccc2)C(=O)Nc3ccc(cc3)[N+]([O-])=O

InChI

1S/C27H34N8O7.C2H4O2/c28-26(29)30-14-4-8-21(24(37)32-19-10-12-20(13-11-19)35(40)41)33-25(38)22-9-5-15-34(22)23(36)16-31-27(39)42-17-18-6-2-1-3-7-18;1-2(3)4/h1-3,6-7,10-13,21-22H,4-5,8-9,14-17H2,(H,31,39)(H,32,37)(H,33,38)(H4,28,29,30);1H3,(H,3,4)/t21-,22-;/m0./s1

InChI key

FPMAXHHYPVIJMC-VROPFNGYSA-N

Description

Application

Z-Gly-Pro-Arg p-nitroanilide acetate salt has been used as a substrate in prostate-specific antigen (PSA) activation protease assay for determining enterokinase-PSA-trypsin (EK-PSA-TRP) activity and to perform kinetic experiments.[1] It has also been used as a substrate to measure the pancreatic trypsin activity chromogenically.[2]

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This Item	P3169	T6140	G1013
Sigma-Aldrich C2276 Z-Gly-Pro-Arg p-nitroanilide acetate salt	Sigma-Aldrich P3169 pGlu-Phe-Leu p-nitroanilide	Sigma-Aldrich T6140 N-(p-Tosyl)-Gly-Pro-Lys 4-nitroanilide acetate salt	Sigma-Aldrich G1013 Gly-Arg 4-methoxy-β-naphthylamide dihydrochloride
assay ≥98% (TLC)	assay ≥98% (TLC)	assay ≥98% (TLC)	assay ≥98% (TLC)
solubility methanol: 20 mg/mL, clear, colorless to light yellow	solubility ethanol: 10 mg/mL, clear, colorless to faintly yellow	solubility ethanol: 50 mg/mL, colorless to yellow	solubility ethanol: 20 mg/mL, clear, colorless to yellow
Quality Level 200	Quality Level 100	Quality Level 200	Quality Level 200
form powder	form powder	form powder	form powder
storage temp. −20°C	storage temp. −20°C	storage temp. −20°C	storage temp. 2-8°C