A5356
N-Me-Abz-Amyloid β/A4 Protein Precursor770 (708-715)-Lys(Dnp)-D-Arg-D-Arg-D-Arg amide trifluoroacetate salt
≥96% (HPLC), lyophilized powder
Synonym(s):
N-Me-Abz-Amyloid β-Protein (37-44)-Lys(Dnp)-D-Arg-D-Arg-D-Arg amide trifluoroacetate salt
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About This Item
Empirical Formula (Hill Notation):
C70H116N26O18 · xC2HF3O2
Molecular Weight:
1609.83 (free base basis)
NACRES:
NA.32
UNSPSC Code:
12352200
Pricing and availability is not currently available.
Quality Level
assay
≥96% (HPLC)
form
lyophilized powder
composition
Peptide content, 92% HPLC
solubility
H2O: >1 mg/mL
shipped in
dry ice
storage temp.
−20°C
Biochem/physiol Actions
A novel intramolecularly quenched fluorescent, presenilin-dependent substrate for assaying γ -secretase activity. It has been used for partial purification and characterization of γ-secretase from post-mortem human brain.
An intramolecularly quenched, fluorescent γ-secretase substrate.
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This Item | |||
|---|---|---|---|
| form lyophilized powder | form powder | form powder | form lyophilized powder |
| assay ≥96% (HPLC) | assay ≥90% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| solubility H2O: >1 mg/mL | solubility - | solubility - | solubility - |
| composition Peptide content, 92% HPLC | composition - | composition - | composition - |
![MCA-[Asn670, Leu671]-Amyloid β/A4 Precursor Protein 770 Fragment 667-676-DNP-Lys-Arg-Arg-NH2 ≥90% (HPLC)](/deepweb/assets/sigmaaldrich/product/images/375/511/f63f11a7-86de-45c4-95a0-7afa616bb265/640/f63f11a7-86de-45c4-95a0-7afa616bb265.jpg)
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Mehmet Fatih Bolukbasi et al.
Molecular therapy. Nucleic acids, 1, e10-e10 (2013-01-25)
Despite intensive studies, the molecular mechanisms by which the genetic materials are uploaded into microvesicles (MVs) are still unknown. This is the first study describing a zipcode-like 25 nucleotide (nt) sequence in the 3'-untranslated region (3'UTR) of mRNAs, with variants
Okay Saydam et al.
Molecular and cellular biology, 29(21), 5923-5940 (2009-08-26)
Meningiomas, one of the most common human brain tumors, are derived from arachnoidal cells associated with brain meninges, are usually benign, and are frequently associated with neurofibromatosis type 2. Here, we define a typical human meningioma microRNA (miRNA) profile and
Global Trade Item Number
| SKU | GTIN |
|---|---|
| A5356-1MG | 04061825655208 |