53727
N-(3-Hydroxydodecanoyl)-DL-homoserine lactone
≥97% (HPLC)
Synonym(s):
3-Hydroxy-N-(tetrahydro-2-oxo-3-furanyl)dodecanamide
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About This Item
Empirical Formula (Hill Notation):
C16H29NO4
CAS Number:
Molecular Weight:
299.41
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
41116134
MDL number:
Pricing and availability is not currently available.
Quality Level
assay
≥97% (HPLC)
composition
carbon, 63.5-64.9% , nitrogen, 4.4-4.9%
storage temp.
−20°C
SMILES string
CCCCCCCCCC(O)CC(=O)NC1CCOC1=O
InChI
1S/C16H29NO4/c1-2-3-4-5-6-7-8-9-13(18)12-15(19)17-14-10-11-21-16(14)20/h13-14,18H,2-12H2,1H3,(H,17,19)
InChI key
RGTXFFYJJNWEPV-UHFFFAOYSA-N
Biochem/physiol Actions
N-(3-Hydroxydodecanoyl)-DL-homoserine lactone is a member of N-acyl-homoserine lactone family. N-Acylhomoserine lactones (AHL) regulate gene expression in gram-negative bacteria, such as Echerichia and Salmonella, and are involved in quorum sensing, cell to cell communication among bacteria; for reviews see[1][2][3][4][5]. Bacterial intercellular communication has become a target for the development of new anti-virulence drugs[3], and a research focus for the prevention of biofilm formation[6][7][8].
Quorum-sensing signal generation
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
1 of 1
This Item | |||
|---|---|---|---|
| assay ≥97% (HPLC) | assay ≥96% (HPLC) | assay - | assay ≥96% (HPLC) |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| composition carbon, 63.5-64.9% | composition carbon, 64.7-67.3% , nitrogen, 4.0-4.5% | composition - | composition - |
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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B M Davis et al.
Biophysical journal, 101(1), 245-254 (2011-07-05)
A practical label-free method for the rapid determination of small-molecule critical micelle concentration (CMC) using a fixed-angle light-scattering technique is described. Change in 90° light scattering at a fixed wavelength of incident radiation with increasing bacterial quorum molecule concentration and
Tommaso R I Cataldi et al.
Journal of mass spectrometry : JMS, 43(1), 82-96 (2007-08-22)
A method for the comprehensive profiling of the N-acyl-homoserine lactone (AHL) family of bacterial quorum-sensing molecules is presented using liquid chromatography (LC) coupled to a hybrid quadrupole linear ion trap (LTQ) and Fourier-transform ion-cyclotron-resonance mass spectrometer (FTICR). We demonstrate an
L Passador et al.
Journal of bacteriology, 178(20), 5995-6000 (1996-10-01)
A series of structural analogs of the Pseudomonas aeruginosa autoinducer [PAI, N-3-oxo-dodecanoyl homoserine lactone] were obtained and tested for their ability to act as autoinducers in stimulating the expression of the gene for elastase (lasB) by measuring beta-galactosidase production from
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 53727-10MG | 04061832860336 |