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Fluorescein dilaurate

Name: Fluorescein dilaurate
Brand: SIGMA

suitable for fluorescence, ≥97.0% (HPCE)

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About This Item

Empirical Formula (Hill Notation):

C₄₄H₅₆O₇

CAS Number:

7308-90-9

Molecular Weight:

696.91

UNSPSC Code:

12352106

NACRES:

NA.32

PubChem Substance ID:

57650888

EC Number:

230-764-2

Beilstein/REAXYS Number:

6034843

MDL number:

MFCD00038409

Pricing and availability is not currently available.

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Properties

Quality Level

100

assay

≥97.0% (HPCE)

form

powder

solubility

ethanol: soluble

fluorescence

λ_ex 490 nm; λ_em 514 nm in 0.1 M Tris pH 8.0 (esterase)

suitability

suitable for fluorescence

SMILES string

CCCCCCCCCCCC(=O)Oc1ccc2c(Oc3cc(OC(=O)CCCCCCCCCCC)ccc3C24OC(=O)c5ccccc45)c1

InChI

1S/C44H56O7/c1-3-5-7-9-11-13-15-17-19-25-41(45)48-33-27-29-37-39(31-33)50-40-32-34(49-42(46)26-20-18-16-14-12-10-8-6-4-2)28-30-38(40)44(37)36-24-22-21-23-35(36)43(47)51-44/h21-24,27-32H,3-20,25-26H2,1-2H3

InChI key

MYTRGBGGRICZGN-UHFFFAOYSA-N

Description

Application

Fluorescein dilaurate is suitable as fluorogenic substrate for esterases/lipases and used in the pancreolauryl test for chronic pancreatitis.

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This Item	88596	46935	86826
Sigma-Aldrich 46943 Fluorescein dilaurate	Sigma-Aldrich 88596 Fluorescein-O′-acetic acid	Sigma-Aldrich 46935 6-[Fluorescein-5(6)-carboxamido]hexanoic acid	Sigma-Aldrich 86826 5-Carboxyfluorescein
suitability suitable for fluorescence	suitability suitable for fluorescence	suitability suitable for fluorescence	suitability suitable for fluorescence
fluorescence λ_ex 490 nm; λ_em 514 nm in 0.1 M Tris pH 8.0 (esterase)	fluorescence λ_ex 455 nm; λ_em 514 nm in 0.1 M Tris pH 8.0	fluorescence λ_ex 491 nm; λ_em 515 nm in 0.1 M Tris pH 9.0	fluorescence λ_ex 492 nm; λ_em 517 nm in 0.1 M Tris pH 8.0
form powder	form powder	form solid	form powder
solubility ethanol: soluble	solubility -	solubility DMF: soluble, DMSO: soluble	solubility DMF: soluble, DMSO: soluble, H₂O: soluble
assay ≥97.0% (HPCE)	assay ≥90% (HPCE)	assay ≥90% (HPCE)	assay ≥95% (HPLC)
Quality Level 100	Quality Level 100	Quality Level 200	Quality Level 100

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Impaired pancreatic function in patients with Crohn's disease with and without pancreatic autoantibodies.

F Seibold et al.

Journal of clinical gastroenterology, 22(3), 202-206 (1996-04-01)

Pancreatic autoantibodies (PABs) are found in 31% of patients with Crohn's disease (CD), but they do not correlate with the activity of intestinal disease or the incidence of acute pancreatitis. Exocrine pancreatic insufficiency has been observed in patients with CD.

[Effect of various methods of resection of the stomach in liberation of cholecystokinin, neurotensin and on pancreatic function].

M Fuchs et al.

Zentralblatt fur Chirurgie, 120(6), 472-477 (1995-01-01)

In a follow up study 19 patients after Billroth-I, 22 patients after Billroth-II-resection and 38 patients after total gastrectomy (23 with Roux-Y-reconstruction and 15 with Longmire-Gütgemann) underwent a stool fat determination and an indirect pancreatic function test with fluorescein dilaurate

Review article: Pancreatic function testing.

R S Chowdhury et al.

Alimentary pharmacology & therapeutics, 17(6), 733-750 (2003-03-19)

Pancreatic function tests are most commonly used to diagnose chronic pancreatitis. These tests include tests which document exocrine or endocrine gland insufficiency and tests which instead measure gradations of decreased secretory capacity. The tests in the former category generally become

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Global Trade Item Number

SKU	GTIN
46943-1G-F	04061826661017
46943-5G-F	04061832532172

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