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14408

N-(+)-Biotinyl-4-aminobenzoic acid

≥98.0% (HPLC)

Synonym(s):

B-PABA

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About This Item

Empirical Formula (Hill Notation):
C17H21N3O4S
CAS Number:
6929-40-4
Molecular Weight:
363.43
NACRES:
NA.79
PubChem Substance ID:
57647153
eCl@ss:
34058011
UNSPSC Code:
12352106
MDL number:
MFCD00077915
Beilstein/REAXYS Number:
50100
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Quality Level

200

assay

≥98.0% (HPLC)

form

powder

optical activity

[α]20/D +55±3°, c = 0.5% in 0.1 M NaOH

color

white to light yellow

mp

295-297 °C

storage temp.

2-8°C

SMILES string

[H][C@]12CS[C@@H](CCCCC(=O)Nc3ccc(cc3)C(O)=O)[C@@]1([H])NC(=O)N2

InChI

1S/C17H21N3O4S/c21-14(18-11-7-5-10(6-8-11)16(22)23)4-2-1-3-13-15-12(9-25-13)19-17(24)20-15/h5-8,12-13,15H,1-4,9H2,(H,18,21)(H,22,23)(H2,19,20,24)/t12-,13-,15-/m0/s1

InChI key

PVMDAMXGKHIMSQ-YDHLFZDLSA-N

Biochem/physiol Actions

Biotinyl-4-aminobenzoic acid (B-PABA) is used as a substrate in biotinidase assays.

Other Notes

Enzyme substrate used in the assay of biotinidase [1][2]

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This Item
A9878133337A6928
N-(+)-Biotinyl-4-aminobenzoic acid ≥98.0% (HPLC)

Sigma-Aldrich

14408

N-(+)-Biotinyl-4-aminobenzoic acid

4-Aminobenzoic acid ReagentPlus®, ≥99%

Sigma-Aldrich

A9878

4-Aminobenzoic acid

4-Acetamidobenzoic acid 98%

Sigma-Aldrich

133337

4-Acetamidobenzoic acid

4-Aminobenzoic acid sodium salt ≥99%, powder

Sigma-Aldrich

A6928

4-Aminobenzoic acid sodium salt

assay

≥98.0% (HPLC)

assay

≥99%

assay

98%

assay

≥99%

form

powder

form

powder

form

powder

form

powder

storage temp.

2-8°C

storage temp.

room temp

storage temp.

-

storage temp.

-

color

white to light yellow

color

-

color

-

color

-

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

mp

295-297 °C

mp

187-189 °C (lit.)

mp

259-262 °C (dec.) (lit.)

mp

300 °C

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
BCCL6970
BCCC8873
BCBW6386
BCBR4332V
BCBM0523V

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D V Craft et al.
Biochemistry, 24(10), 2471-2476 (1985-05-07)
Biotinidase catalyzes the hydrolysis of N epsilon-biotinyllysine (biocytin) to form biotin and free lysine. The enzyme has been purified 4800-fold from outdated human plasma and was determined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis to have a molecular weight of (76
Determination of biotinidase activity by liquid chromatography with fluorimetric detection.
K Hayakawa et al.
Journal of chromatography, 383(1), 148-152 (1986-11-28)
Keyna A Kobza et al.
The Journal of nutritional biochemistry, 19(12), 826-832 (2008-05-16)
Posttranslational modification of histones by biotinylation can be catalyzed by both biotinidase (BTD) and holocarboxylase synthetase. Biotinylation of histones is an important epigenetic mechanism to regulate gene expression, DNA repair, and chromatin remodeling. The role of BTD in histone biotinylation
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Global Trade Item Number

SKUGTIN
537764-5G04061837581946
14408-10MG04061833267899
14408-50MG04061838735355

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