840035C

18:1 PS (DOPS)

Avanti Research^™ - A Croda Brand

• Sinonimo/i: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine (sodium salt); DOPS; PS(18:1(9Z)/18:1(9Z))
• Formula empirica (notazione di Hill): C₄₂H₇₇NO₁₀PNa
• Numero CAS: 90693-88-2
• Peso molecolare: 810.03
• Codice UNSPSC: 51191904
• NACRES: NA.25

Proprietà

• Descrizione: 1,2-dioleoyl-sn-glycero-3-phospho-L-serine (sodium salt), chloroform
• Saggio: >99% (TLC)
• Stato: liquid
• Confezionamento: pkg of 1 × 1 mL (840035C-10mg); pkg of 1 × 2.5 mL (840035C-25mg); pkg of 2 × 4 mL (840035C-200mg); pkg of 5 × 4 mL (840035C-500mg)
• Produttore/marchio commerciale: Avanti Research^™ - A Croda Brand
• Concentrazione: 10 mg/mL (840035C-10mg); 10 mg/mL (840035C-25mg); 25 mg/mL (840035C-200mg); 25 mg/mL (840035C-500mg)
• Tipo di lipide: cardiolipins; phospholipids
• Condizioni di spedizione: dry ice
• Temperatura di conservazione: −20°C
• Stringa SMILE: [H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[Na+]
• InChI: 1S/C42H78NO10P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-40(44)50-35-38(36-51-54(48,49)52-37-39(43)42(46)47)53-41(45)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h17-20,38-39H,3-16,21-37,43H2,1-2H3,(H,46,47)(H,48,49);/q;+1/p-1/b19-17-,20-18-;/t38-,39+;/m1./s1; KPHZNDUWYZIXFY-YORIBCANSA-M

Descrizione

Descrizione generale

DOPS is an excellent substitute for the naturally occurring Brain PS. It has similar physical properties and is more stable to oxidation. DOPS has been used, along with DOPC and DOPE, in lipid mixtures to mimic platelet membranes for coagulation studies.

Phosphoserine/phosphatidylserine (PS) is an endogenous phospholipid,[1] that is found in all polyanionic macromolecules.[2] 1,2-dioleoyl-sn-glycero-3-phospho-L-serine (DOPS) carry a carboxylic acid group and a protonated amine group in their head group.[3]

Applicazioni

18:1 PS (DOPS) has been used as a component of supported membrane tubes (SMrT) templates.[4] It has also been used in the preparation of lipid-mixing vesicles, content-mixing vesicles and lipid mixture.[5]

Azioni biochim/fisiol

Phosphoserine (PS) can be used as a template for the recognition of cancer antigen 125 (CA 125).[6] It is very essential for healthy nerve cell membranes and myelin.[1] Exogenous PS can be actively absorbed in humans. It plays a key role in the formation of short-term memory, the consolidation of long-term memory, the ability to create new memories and several other cognitive activities. It actively participates in the locomotor functions, like rapid reactions and reflexes.[1]

Confezionamento

30 mL Amber Narrow Mouth Bottle with Screw Cap (840035C-500mg)

5 mL Clear Glass Sealed Ampule (840035C-10mg)

5 mL Clear Glass Sealed Ampule (840035C-200mg)

5 mL Clear Glass Sealed Ampule (840035C-25mg)

Note legali

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Informazioni sulla sicurezza

• Pittogrammi: GHS06,GHS08
• Avvertenze: Danger
• Indicazioni di pericolo: H302,H315,H319,H331,H336,H351,H361d,H372,H412
• Consigli di prudenza: P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313
• Classi di pericolo: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
• Organi bersaglio: Central nervous system, Liver,Kidney
• Codice della classe di stoccaggio: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable