850345C

14:0 PC (DMPC)

1,2-dimyristoyl-sn-glycero-3-phosphocholine, chloroform

• Sinonimo/i: 1,2-ditetradecanoyl-sn-glycero-3-phosphocholine; DMPC; PC(14:0/14:0)
• Formula empirica (notazione di Hill): C₃₆H₇₂NO₈P
• Numero CAS: 18194-24-6
• Peso molecolare: 677.93
• Codice UNSPSC: 51191904
• NACRES: NA.25

Proprietà

• Saggio: >99% (TLC)
• Forma fisica: liquid
• Confezionamento: pkg of 1 × 2.5 mL (850345C-25mg); pkg of 1 × 20 mL (850345C-500mg); pkg of 2 × 20 mL (850345C-1g); pkg of 2 × 4 mL (850345C-200mg)
• Produttore/marchio commerciale: Avanti Research^™ - A Croda Brand 850345C
• Concentrazione: 10 mg/mL (850345C-25mg); 25 mg/mL (850345C-1g); 25 mg/mL (850345C-200mg); 25 mg/mL (850345C-500mg)
• Tipo di lipide: phospholipids; cardiolipins
• Condizioni di spedizione: dry ice
• Temperatura di conservazione: −20°C
• InChI: 1S/C36H72NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-35(38)42-32-34(33-44-46(40,41)43-31-30-37(3,4)5)45-36(39)29-27-25-23-21-19-17-15-13-11-9-7-2/h34H,6-33H2,1-5H3/t34-/m0/s1; CITHEXJVPOWHKC-UMSFTDKQSA-N

Descrizione

Descrizione generale

Phosphatidylcholine (PC) is a strong bilayer-forming lipid. It the most common phospholipid in mammalian membranes. It is also an important component of the mucosal layer of the colon.

The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Applicazioni

14:0 PC (DMPC) has been used in liposome preparation. It is also suitable for use:

• in the preparation of lipid bicelles for nuclear magnetic resonance (NMR) experiments
• in labeled vesicle preparation for fluorescence polarization measurements
• as internal standard (IS) for the quantitation of phosphatidylcholine (PC) by liquid chromatography with tandem mass spectrometry (LC-MS-MS)

Azioni biochim/fisiol

Phosphatidylcholine (PC) functions as a surfactant within the mucus to form a hydrophobic surface to inhibit bacterial penetrance. It is used to treat fat embolism. Phosphatidylcholine lowers the levels of cholesterol and triglycerides.

Confezionamento

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (850345C-1g)

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (850345C-500mg)

5 mL Clear Glass Sealed Ampule (850345C-200mg)

5 mL Clear Glass Sealed Ampule (850345C-25mg)

Note legali

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Informazioni sulla sicurezza

• Pittogrammi: GHS06,GHS08
• Avvertenze: Danger
• Indicazioni di pericolo: H302,H315,H319,H331,H336,H351,H361d,H372,H412
• Consigli di prudenza: P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313
• Classi di pericolo: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
• Organi bersaglio: Central nervous system, Liver,Kidney
• Codice della classe di stoccaggio: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): does not flash
• Punto d’infiammabilità (°C): does not flash