1091108

Capsaicin

United States Pharmacopeia (USP) Reference Standard

• Szinonimák: 8-Methyl-N-vanillyl-trans-6-nonenamide
• Lineáris képlet: (CH₃)₂CHCH=CH(CH₂)₄CONHCH₂C₆H₃-4-(OH)-3-(OCH₃)
• CAS-szám: 404-86-4
• Molekulatömeg: 305.41
• Beilstein: 2816484
• MDL-szám: MFCD00017259
• UNSPSC kód: 41116107
• PubChem Substance ID: 329749225
• NACRES: NA.24

Tulajdonságok

• grade: pharmaceutical primary standard
• API-család: capsaicin
• gyártó/kereskedő neve: USP
• mp: 62-65 °C (lit.)
• alkalmazás(ok): pharmaceutical (small molecule)
• Formátum: neat
• tárolási hőmérséklet: 2-8°C
• SMILES string: COc1cc(CNC(=O)CCCC\C=C\C(C)C)ccc1O
• InChI: 1S/C18H27NO3/c1-14(2)8-6-4-5-7-9-18(21)19-13-15-10-11-16(20)17(12-15)22-3/h6,8,10-12,14,20H,4-5,7,9,13H2,1-3H3,(H,19,21)/b8-6+
• Nemzetközi kémiai azonosító kulcs: YKPUWZUDDOIDPM-SOFGYWHQSA-N
• Géninformáció: human ... TRPV1(7442)

Leírás

Általános leírás

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Alkalmazás

Capsaicin USP reference standard for use in specified quality tests and assays.

Also used to prepare standard solutions for the assay, identification, composition and strength analysis according to the given below monographs of United States Pharmacopeia (USP):

• Capsaicin
• Capsicum Oleoresin
• Capsicum
• Ginger Tincture

Biokémiai/fiziológiai hatások

Prototype vanilloid receptor agonist. Neurotoxin; activates sensory neurons that give rise to unmyelinated C-fibers, many of which contain substance P. Topical application desensitizes the sensory nerve endings giving a paradoxical antinociceptive effect; systemic administration can be neurotoxic to capsaicin-sensitive cells, especially in newborn animals. Active component of chili peppers.

Prototype vanilloid receptor agonist; neurotoxin. Active component of chili peppers.

Analízis megjegyzés

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Egyéb megjegyzések

Sales restrictions may apply.

Biztonsági adatok

• Piktogramok: GHS06,GHS08,GHS05
• Figyelmeztetés: Danger
• Figyelmeztető mondatok: H300,H315,H317,H318,H334,H335
• Óvintézkedésre vonatkozó mondatok: P280 - P301 + P310 + P330 - P302 + P352 - P305 + P351 + P338 + P310
• Veszélyességi osztályok: Acute Tox. 2 Oral - Eye Dam. 1 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• Célzott szervek: Respiratory system
• Tárolási osztály kódja: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Lobbanási pont (F): 235.4 °F - closed cup
• Lobbanási pont (C): 113 °C - closed cup