Összes fotó(1)
Fontos dokumentumok
N0513
Nerve Growth Factor-7S from murine submaxillary gland
lyophilized powder, suitable for cell culture
Szinonimák:
NGF-7S
Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez
Összes fotó(1)
About This Item
Javasolt termékek
product name
Nerve Growth Factor-7S from murine submaxillary gland, NGF-7S, lyophilized powder, suitable for cell culture
biológiai forrás
mouse
Minőségi szint
form
lyophilized powder
hatékonyság
2-250 ng/mL ED50/EC50
minőség
endotoxin tested
molekulatömeg
protein 130 kDa
kiszerelés
pkg of 0.1 mg
technika/technikák
cell culture | mammalian: suitable
szennyeződések
≤10
szín
white
UniProt elérési szám
tárolási hőmérséklet
−20°C
Géninformáció
mouse ... Ngf(18049)
Általános leírás
Nerve growth factor (NGF) is a dimer of 118-residue polypeptide chains linked non-covalently. Both these polypeptides contain three intramolecular disulphide bridges. It forms the prototype of the neurotrophin growth factor family. In male mouse submandibular salivary gland, NGF is present in high amounts, and is present as a high molecular weight complex called nerve growth factor-7S (NGF-7S). NGF-7S is an α2β2γ2 complex, where β2-NGF is the active neurotrophin, and is linked to the dimers of the glandular kallikrein serine proteinases members, α-NGF and γ-NGF.
Alkalmazás
Nerve Growth Factor-7S (NGF-7S) from murine submaxillary gland has been used for the treatment of following cells to induce neuronal differentiation-
- PC12
- Dorsal root ganglia (DRG) obtained from chick embryos of either sex (Gallus gallus)
Biokémiai/fiziológiai hatások
Nerve growth factor (NGF) is a neurotrophin, which facilitates the differentiation and survival of specific subtypes of neurons of central nervous system and peripheral nervous system. However, nerve growth factor-7S (NGF-7S) lacks any neurotrophic activity as most part of β-NGF subunit is buried within the NGF-7S complex.
Fizikai forma
Lyophilized from 0.2 μm filtered solution in 25 mM sodium phosphate, pH 7.0.
Elkészítési megjegyzés
Nerve growth factor-7S (NGF-7S) is isolated from male mouse submaxillary glands using a modification of the method of Varon, et al.
Analízis megjegyzés
The biological activity is measured using a 3-day MTT assay.
Tárolási osztály kódja
11 - Combustible Solids
WGK
WGK 3
Lobbanási pont (F)
Not applicable
Lobbanási pont (C)
Not applicable
Egyéni védőeszköz
Eyeshields, Gloves, type N95 (US)
Analitikai tanúsítványok (COA)
Analitikai tanúsítványok (COA) keresése a termék sarzs-/tételszámának megadásával. A sarzs- és tételszámok a termék címkéjén találhatók, a „Lot” vagy „Batch” szavak után.
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