Összes fotó(1)
Fontos dokumentumok
N6009
Nerve Growth Factor-2.5S from murine submaxillary gland
lyophilized powder, suitable for cell culture
Szinonimák:
NGF-2.5S
Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez
Összes fotó(1)
About This Item
Javasolt termékek
product name
Nerve Growth Factor-2.5S from murine submaxillary gland, NGF-2.5S, lyophilized powder, suitable for cell culture
biológiai forrás
mouse
Minőségi szint
form
lyophilized powder
hatékonyság
0.1-30 ng/mL EC50 (using PC-12 cells)
molekulatömeg
26.5 kDa
kiszerelés
pkg of 4X25 μg
tárolási körülmény
avoid repeated freeze/thaw cycles
technika/technikák
cell culture | mammalian: suitable
UniProt elérési szám
kiszállítva
dry ice
tárolási hőmérséklet
−20°C
Géninformáció
mouse ... Ngf(18049)
Általános leírás
Nerve growth factor (NGF) is produced by different cell types: structural, accessory, and immune cells. It belongs to the neurotrophin family of trophic factors.
Alkalmazás
Nerve Growth Factor-2.5S from murine submaxillary gland has been used:
- in Ham′s F-12 medium for performing growth cone collapse assay using dorsal root ganglions (DRGs)
- as a media supplement in the “process compartment” for microfluidic chamber studies
- to treat mid-luteal cells to study its effect on choline acetyltransferase (CHAT) expression
Biokémiai/fiziológiai hatások
Nerve growth factor (NGF) is neurotrophic and maintains sympathetic and sensory neurons of the peripheral nervous system and forebrain cholinergic neurons. NGF promotes the development of neurite-like filaments from chick embryo dorsal root ganglia and rat PC12 pheochromocytoma cells. NGF may have a role in in vivo fetal development and nerve regeneration especially, after ischemic, surgical, or chemical injuries. NGF may also be associated with the central nervous system. It exhibits ameliorating effects against ulcers (human cutaneous, corneal ulcers, and pressure ulcers), glaucoma, maculopathy, and retinitis pigmentosa. NGF-2.5S is a type of NGF-b originally derived under dissociative conditions and often varies from NGF-b due to proteolysis arising during its purification.
Egyéb megjegyzések
2.5S subunit of nerve growth factor-7S (NGF-7S) is essentially the β-subunit when isolated from male mouse submaxillary glands under initially dissociative conditions by a modification of the method of Bocchini and Angeletti.
Fizikai forma
Lyophilized from a 0.2 μm filtered solution in sodium acetate buffer.
Analízis megjegyzés
The biological activity is measured using a 3-day MTT assay.
Tárolási osztály kódja
11 - Combustible Solids
WGK
WGK 3
Lobbanási pont (F)
Not applicable
Lobbanási pont (C)
Not applicable
Egyéni védőeszköz
Eyeshields, Gloves, type N95 (US)
Analitikai tanúsítványok (COA)
Analitikai tanúsítványok (COA) keresése a termék sarzs-/tételszámának megadásával. A sarzs- és tételszámok a termék címkéjén találhatók, a „Lot” vagy „Batch” szavak után.
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