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L2654

Sigma-Aldrich

Lipopolysaccharides from Escherichia coli O26:B6

γ-irradiated, BioXtra, suitable for cell culture

Szinonimák:

LPS

Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez
Összes fotó(2)

About This Item

EC-szám:
297-473-0
MDL-szám:
MFCD00164401
UNSPSC kód:
12352211
NACRES:
NA.75

biológiai forrás

Escherichia coli (O26:B6)

Minőségi szint

300

sterilitás

γ-irradiated

termékcsalád

BioXtra

form

lyophilized powder

tisztítva

gel-filtration chromatography

technika/technikák

cell culture | mammalian: suitable

szennyeződések

<5% Protein (Lowry)

oldhatóság

H2O: 5 mg/mL, slightly hazy

tárolási hőmérséklet

2-8°C

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Alkalmazás

Lipopolysaccharides from Escherichia coli 026:B6 was used to elicit the secretion of cytokines by human PBMC, murine bone marrow dendritic cells and rat astrocytes.
Lipopolysaccharides (LPSs) are characteristic components of the cell wall of Gram-negative bacteria. LPS and its lipid A moiety stimulate cells of the innate immune system by the Toll-like receptor 4 (TLR4), a member of the Toll-like receptor protein family, which recognizes common pathogen-associated molecular-patterns (PAMPs).

Biokémiai/fiziológiai hatások

LPS is a major constituent of the cell wall of most gram negative bacteria. It is a highly immunogenic antigen with the ability to enhance immune responses to soluble antigens. LPS also acts as a specific mitogen for bone marrow derived B lymphocytes from mice, rabbits, chickens, cows, hamsters, and humans.

Feloldás

Lipopolysaccharides are supplied as lyophilized, γ-irradiated powders. To reconstitute, add 1 ml sterile balanced salt solution or tissue culture medium to the vial (1 mg) and gently swirl until the powder dissolves. Reconstituted product may be further diluted to desired working concentrations using sterile balanced salt solution or tissue culture medium.

Egyéb megjegyzések

To gain a comprehensive understanding of our extensive range of Lipopolysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Piktogramok

Skull and crossbones
GHS06

Figyelmeztetés

Danger

Figyelmeztető mondatok

H300

Óvintézkedésre vonatkozó mondatok

P264 - P270 - P301 + P310 - P405 - P501

Veszélyességi osztályok

Acute Tox. 2 Oral

Tárolási osztály kódja

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Lobbanási pont (F)

Not applicable

Lobbanási pont (C)

Not applicable

Analitikai tanúsítványok (COA)

Analitikai tanúsítványok (COA) keresése a termék sarzs-/tételszámának megadásával. A sarzs- és tételszámok a termék címkéjén találhatók, a „Lot” vagy „Batch” szavak után.

Már rendelkezik ezzel a termékkel?

Az Ön által nemrégiben megvásárolt termékekre vonatkozó dokumentumokat a Dokumentumtárban találja.

Dokumentumtár megtekintése

Ø Salvesen et al.
Journal of neuroinflammation, 14(1), 106-106 (2017-05-24)
The cellular prion protein (PrP In order to explore putative roles for PrP All LPS-treated goats displayed clinical signs of sickness behavior, which were of significantly (p < 0.01) longer duration in animals without PrP Our data suggest that PrP
David Gozal et al.
Sleep, 33(3), 319-325 (2010-03-27)
Sleep disordered breathing in children is associated with severity-dependent increases in excessive daytime sleepiness (EDS). TNF-alpha is an inflammatory cytokine that has been implicated in EDS. Since, at any given level of apnea-hypopnea index, there is significant variability in EDS
S Ménard et al.
Gut, 53(6), 821-828 (2004-05-13)
Probiotic bacteria have a beneficial effect on intestinal inflammation. In this study, we have examined the effect of lactic acid and commensal Gram positive (+) bacteria conditioned media (CM) on tumour necrosis factor alpha (TNF-alpha) release and the mechanisms involved.
Peta J O'Connell et al.
Blood, 107(3), 1010-1017 (2005-10-15)
Adaptive immunity is triggered at the immune synapse, where peptide-major histocompatibility complexes and costimulatory molecules expressed by dendritic cells (DCs) are physically presented to T cells. Here we describe transmission of the inflammatory monoamine serotonin (5-hydroxytryptamine [5-HT]) between these cells.
Asad Ali et al.
The Journal of steroid biochemistry and molecular biology, 180, 73-80 (2018-02-07)
Emerging evidence suggests that maternal or developmental vitamin D (DVD) deficiency is a risk factor for Autism Spectrum Disorders. A well-established association has also been found between gestational infection and increased incidence of autism. Placenta mediates the maternal immune response
View All Related Papers

Cikkek

Lipopolysaccharides for Research – Structure, Function & Applications

Explore the structure, function, and diverse applications of Lipopolysaccharides. Discover their role in bacteria, serological specificity, and research potential.

Tudóscsoportunk valamennyi kutatási területen rendelkezik tapasztalattal, beleértve az élettudományt, az anyagtudományt, a kémiai szintézist, a kromatográfiát, az analitikát és még sok más területet.

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