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H7166

Sigma-Aldrich

IL-3 human

HumanKine®, recombinant, Xeno-free, >95% (SDS-PAGE), suitable for cell culture

Szinonimák:

IL-3

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About This Item

MDL-szám:
MFCD00147276
UNSPSC kód:
12352202
NACRES:
NA.77

product name

Interleukin-3 human, IL-3, recombinant, expressed in HEK 293 cells, HumanKine®, suitable for cell culture

biológiai forrás

human

Minőségi szint

100

rekombináns

expressed in HEK 293 cells

Teszt

>95% (SDS-PAGE)

form

lyophilized powder

hatékonyság

≤2 ng/mL EC50

minőség

endotoxin tested

molekulatömeg

dimer 17-45 kDa (glycosylated)

kiszerelés

pkg of 10 μg

gyártó/kereskedő neve

HumanZyme

technika/technikák

cell culture | mammalian: suitable

szennyeződések

<1 EU/μg

UniProt elérési szám

P08700

tárolási hőmérséklet

−20°C

Géninformáció

human ... IL3(3562)

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Biokémiai/fiziológiai hatások

Interleukin-3 (IL-3) is a multifunctional protein, originally called colony forming unit-stimulating activity (CFU-SA), and is produced by activated T lymphocytes. IL-3 supports the formation of multilineage colonies in the early development of multipotent hematopoietic progenitor cells. IL-3 has been shown to induce colony formation of macrophages, neutrophils, mast cells, and megakaryocytes from agar-suspended bone marrow cells. IL-3 also interacts with IL-2 to stimulate growth of T lymphocytes and to induce IgG secretion from activated B cells. Other synonyms for IL-3 include pan-specific hemopoietin, multicolony stimulating factor, mast cell growth factor, burst promoting activity, histamine-producing cell stimulating factor, P cell stimulating factor, and WEHI-3 factor.

Fizikai forma

Lyophilized from a 0.2 μm filtered solution of 1x PBS.

Elkészítési megjegyzés

HumanKine Interleukin-3 (IL-3), expressed in human HEK 293 cells, is a glycosylated monomer with an apparent molecular mass of 17-45 kDa due to glycosylation, which is absent when this cytokine is expressed in E. coli. Production in human HEK 293 cells offers authentic glycosylation which contributes to stability in cell growth media and other applications.

Analízis megjegyzés

The activity was determined by the dosedependent stimulation of the proliferation of human TF-1 cells (human erythroleukemic indicator cell line).

Jogi információk

HumanKine is a registered trademark of Proteintech Group, Inc. and Humanzyme, Inc

Tárolási osztály kódja

11 - Combustible Solids

WGK

WGK 3

Lobbanási pont (F)

Not applicable

Lobbanási pont (C)

Not applicable

Analitikai tanúsítványok (COA)

Analitikai tanúsítványok (COA) keresése a termék sarzs-/tételszámának megadásával. A sarzs- és tételszámok a termék címkéjén találhatók, a „Lot” vagy „Batch” szavak után.

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Sodium butyrate 98%

Sigma-Aldrich

303410

Sodium butyrate

Sodium butyrate &#8805;98.5% (GC)

Sigma-Aldrich

B5887

Sodium butyrate

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