Összes fotó(5)
Fontos dokumentumok
C7752
Cytochrome c from equine heart
≥95% based on Mol. Wt. 12,384 basis
Szinonimák:
Cytochrome c from horse heart
Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez
Összes fotó(5)
About This Item
Javasolt termékek
biológiai forrás
horse heart
Minőségi szint
Teszt
≥95% (SDS-PAGE)
≥95% based on Mol. Wt. 12,384 basis
Forma
powder
molekulatömeg
12,384
technika/technikák
cell culture | mammalian: suitable
alkalmasság
suitable for molecular biology
UniProt elérési szám
tárolási hőmérséklet
−20°C
Géninformáció
horse ... CYCS(100053958)
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Alkalmazás
Cytochrome c is used as an inducer of mitochondria-dependent apoptosis in various research studies. The identification and monitoring of oxidation sites in cytochrome c may have implications for assessing oxidative stress-related conditions and diseases. It could potentially be used as a biomarker to evaluate the extent of oxidative damage and the antioxidant capacity of cells and tissues.
Cytochrome c is suitable for use as a component of phosphate buffer for the detection and evaluation of complex IV activity using blue-native gel electrophoresis (BN-PAGE). It may also be used for the detection of extracellular superoxide anion (ECSA) in isolated kidney phagocytes.
Cytochrome c is suitable for use as a component of phosphate buffer for the detection and evaluation of complex IV activity using blue-native gel electrophoresis (BN-PAGE). It may also be used for the detection of extracellular superoxide anion (ECSA) in isolated kidney phagocytes.
The specific sites and extent of oxidation in horse cytochrome c treated with H2O2 and UV were characterized. It was suggested that the state of these sites could be used as a biomarker for the oxidative environment in a cell.
Biokémiai/fiziológiai hatások
Cytochrome c has been identified as an important mediator in apoptotic pathways. The release of mitochondrial cytochrome c into the cytoplasm stimulates apoptosis and is commonly used as an indicator of the apoptotic process in the cell.
Cytochrome c is primarily known as an electron-carrying mitochondrial protein. The transition of cytochrome c between the ferrous and ferric states within the cell makes it an efficient biological electron-transporter and it plays a vital role in cellular oxidations in both plants and animals. It is generally regarded as a universal catalyst of respiration, forming an essential electron-bridge between the respirable substrates and oxygen
Elkészítési megjegyzés
Prepared with acetic acid without using TCA.
Egyéb megjegyzések
View more information on cytochrome c and electron transport at www.sigma-aldrich.com/enzymeexplorer.
Alkalmazás
gyakran vásárolják ezzel a termékkel együtt
Product No.
Leírás
Árazás
Tárolási osztály kódja
11 - Combustible Solids
WGK
WGK 3
Lobbanási pont (F)
Not applicable
Lobbanási pont (C)
Not applicable
Egyéni védőeszköz
Eyeshields, Gloves, type N95 (US)
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Protocols
Enzymatic Assay of Superoxide Dismutase
Chromatograms
application for HPLCapplication for HPLCapplication for HPLCTudóscsoportunk valamennyi kutatási területen rendelkezik tapasztalattal, beleértve az élettudományt, az anyagtudományt, a kémiai szintézist, a kromatográfiát, az analitikát és még sok más területet.
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