84510

Saponin

used as non-ionic surfactant

• Szinonimák: glycosides, saponins
• CAS-szám: 8047-15-2
• EC-szám: 232-462-6
• MDL-szám: MFCD00081981
• UNSPSC kód: 12161900
• NACRES: NA.25

Tulajdonságok

• biológiai forrás: plant (Quillaya)
• Minőségi szint: 300
• Forma: powder
• összetétel: Sapogenin, 8-25%
• környezetbarátabb alternatív termék tulajdonságai: Less Hazardous Chemical Syntheses; Use of Renewable Feedstocks; Learn more about the Principles of Green Chemistry.
• sustainability: Greener Alternative Product
• technika/technikák: HPLC: suitable; protein quantification: suitable
• szennyeződések: ≤20% sulphated ash
• CMC: 0.001-0.01%
• oldhatóság: water: 1 g/10 mL, clear to hazy, yellow to brown
• sűrűség: 1.015-1.020 g/mL at 20 °C (5% in H₂O)(lit.)
• környezetbarátabb alternatív kategória: Aligned
• SMILES string: C[C@]1(CCC23COC4([C@H]2C1)CC[C@@H]5[C@]6(CC[C@@H](C(C6CC[C@]5([C@@]4(C[C@H]3O)C)C)(C)C)O[C@H]7[C@@H]([C@H]([C@H](CO7)O[C@H]8[C@@H]([C@H]([C@@H](CO8)O)O)O)O[C@@H]9[C@@H]([C@H]([C@@H]([C@H](O9)CO)O)O)O)O[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O[C@@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O)C)C=O
• InChI: 1S/C58H94O27/c1-52(2)29-7-11-55(5)30(8-12-58-31-15-53(3,22-62)13-14-57(31,23-77-58)32(64)16-56(55,58)6)54(29,4)10-9-33(52)82-50-46(85-51-45(40(71)37(68)27(19-61)80-51)84-49-43(74)39(70)36(67)26(18-60)79-49)44(83-48-42(73)38(69)35(66)25(17-59)78-48)28(21-76-50)81-47-41(72)34(65)24(63)20-75-47/h22,24-51,59-61,63-74H,7-21,23H2,1-6H3/t24-,25-,26-,27-,28+,29?,30-,31+,32-,33+,34+,35-,36-,37-,38+,39+,40+,41-,42-,43-,44+,45-,46-,47+,48-,49-,50+,51+,53-,54+,55-,56+,57?,58?/m1/s1
• Nemzetközi kémiai azonosító kulcs: MAEBCGDGGATMSC-OSHGGGOQSA-N

Leírás

Általános leírás

Canonical SMILES: CC1(C2CCC3(C(C2(CCC1OC4C(C(C(CO4)OC5C(C(C(CO5)O)O)O)OC6C(C(C(C(O6)CO)O)O)O)OC7C(C(C(C(O7)CO)O)O)OC8C(C(C(C(O8)CO)O)O)O)C)CCC91C3(CC(C2(C9CC(CC2)(C)C=O)CO1)O)C)C)C

Saponins, belonging to the class of steroid or triterpenoid glycosides, are widely distributed in plants, marine animals, and certain bacteria, serving as crucial compounds in various research fields, including biochemical, cell biology, and beyond. These amphipathic glycosides exhibit soap-like foaming in aqueous solutions due to their distinctive structure, featuring hydrophilic glycoside moieties combined with a lipophilic triterpene derivative.

Beyond their structural uniqueness, saponins play essential roles in biochemical processes, acting as secondary metabolites that facilitate protein penetration through cell membranes. Studies indicate their amphipathic nature and potential as hemolytic agents, contributing to their utility in immunoassays by stimulating the Th1 immune response and cytotoxic T-lymphocyte production. In cell biology, saponins find applications as nonionic surfactants, influencing cellular processes and interactions.

Moreover, saponins serve as promising components in vaccine research, functioning as adjuvants that can activate the mammalian immune system. This property, combined with their ability to solubilize low-density lipoproteins and regulate cholesterol concentration in micelles, makes saponins versatile and valuable in multidisciplinary research areas, including biochemical and cell biology research.

We are committed to bringing you greener alternative products, which adhere to one or more of the 12 Principles of Green Chemistry. This product is Bio-based and thus aligns with ″Use of Renewable Feedstocks″.

Alkalmazás

Saponin has been used:

• as a wetting agent to study its effects on the floatability of six plastics
• to permeabilize washed neutrophils for immunofluorescence
• as a supplement in phosphate buffer saline (PBS) for immunocytochemistry

Glycoside used as a nonionic sufactant and adjuvant in vaccine development.

Biokémiai/fiziológiai hatások

Saponins are nonionic surfactant that forms oil-in-water emulsions and acts as a protective colloid. They are used for the direct determination of metals in milk by flame atomic absorption spectrophotometry.

Tulajdonságok és előnyök

• Suitable for Biochemical and Cell Biology research
• Can be used with HPLC and Protein Quantification
• High purity product for research applications

Egyéb megjegyzések

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Biztonsági adatok

• Piktogramok: GHS07
• Figyelmeztetés: Warning
• Figyelmeztető mondatok: H319,H335
• Óvintézkedésre vonatkozó mondatok: P261 - P264 - P271 - P280 - P304 + P340 + P312 - P305 + P351 + P338
• Veszélyességi osztályok: Eye Irrit. 2 - STOT SE 3
• Célzott szervek: Respiratory system
• Tárolási osztály kódja: 11 - Combustible Solids
• WGK: WGK 2
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable
• Egyéni védőeszköz: dust mask type N95 (US), Eyeshields, Gloves