Y0000457

Repaglinide

European Pharmacopoeia (EP) Reference Standard

• Szinonimák: (S)-(+)-2-Ethoxy-4-[N-[1-(2-piperidinophenyl)-3-methyl-1-butyl]aminocarbonylmethyl]benzoic acid, Novonorm, Prandin
• Tapasztalati képlet (Hill-képlet): C₂₇H₃₆N₂O₄
• CAS-szám: 135062-02-1
• Molekulatömeg: 452.59
• MDL-szám: MFCD00906179
• UNSPSC kód: 41116107
• PubChem Substance ID: 329830967
• NACRES: NA.24

Tulajdonságok

• grade: pharmaceutical primary standard
• API-család: repaglinide
• gyártó/kereskedő neve: EDQM
• alkalmazás(ok): pharmaceutical (small molecule)
• Formátum: neat
• tárolási hőmérséklet: 2-8°C
• SMILES string: CCOc1cc(CC(=O)N[C@@H](CC(C)C)c2ccccc2N3CCCCC3)ccc1C(O)=O
• InChI: 1S/C27H36N2O4/c1-4-33-25-17-20(12-13-22(25)27(31)32)18-26(30)28-23(16-19(2)3)21-10-6-7-11-24(21)29-14-8-5-9-15-29/h6-7,10-13,17,19,23H,4-5,8-9,14-16,18H2,1-3H3,(H,28,30)(H,31,32)/t23-/m0/s1
• Nemzetközi kémiai azonosító kulcs: FAEKWTJYAYMJKF-QHCPKHFHSA-N
• Géninformáció: human ... ABCC8(6833) , KCNJ11(3767)

Leírás

Általános leírás

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Alkalmazás

Repaglinide EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biokémiai/fiziológiai hatások

Repaglinide is a potent short-acting insulin secretagogue that acts by closing ATP-sensitive potassium (K_ATP) channels in the plasma membrane of the pancreatic beta cell. It represents a new class of insulin secretagogues, structurally unrelated to sulphonylureas, which were developed for the treatment of type 2 diabetes.

Kiszerelés

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Egyéb megjegyzések

Sales restrictions may apply.

Biztonsági adatok

• Tárolási osztály kódja: 11 - Combustible Solids
• WGK: WGK 2
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable