PHR1199

Glucosamine hydrochloride

Pharmaceutical Secondary Standard; Certified Reference Material

• Szinonimák: D-(+)-Glucosamine hydrochloride, GLH, 2-Amino-2-deoxy-D-glucose hydrochloride, Chitosamine hydrochloride
• Tapasztalati képlet (Hill-képlet): C₆H₁₃NO₅ · HCl
• CAS-szám: 66-84-2
• Molekulatömeg: 215.63
• Beilstein: 4157370
• MDL-szám: MFCD00135831
• UNSPSC kód: 41116107
• PubChem Substance ID: 329823206
• NACRES: NA.24

Tulajdonságok

• grade: certified reference material; pharmaceutical secondary standard
• Minőségi szint: 300
• Ügynökség: traceable to Ph. Eur. Y0001406; traceable to USP 1294207
• API-család: glucosamine
• Analitikai műbizonylat: current certificate can be downloaded
• technika/technikák: HPLC: suitable; gas chromatography (GC): suitable
• mp: 190-194 °C (dec.) (lit.)
• alkalmazás(ok): pharmaceutical (small molecule)
• format: neat
• tárolási hőmérséklet: 2-30°C
• SMILES string: Cl.N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O
• InChI: 1S/C6H13NO5.ClH/c7-3-5(10)4(9)2(1-8)12-6(3)11;/h2-6,8-11H,1,7H2;1H/t2-,3-,4-,5-,6?;/m1./s1
• Nemzetközi kémiai azonosító kulcs: QKPLRMLTKYXDST-NSEZLWDYSA-N

Leírás

Általános leírás

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Glucosamine hydrochloride is a drug prescribed for the remediation of degenerative joint diseases in small animals.

Alkalmazás

Glucosamine hydrochloride may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations and plasma samples by high performance liquid chromatography (HPLC).

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Biokémiai/fiziológiai hatások

Glucosamine, an amino sugar, is the precursor of the hexosamine biosynthetic pathway leading to the formation of UDP-N-acetylglucosamine (UDP-GlcNAc), which is then used for making glycosaminoglycans, proteoglycans, and glycolipids. D-(+)-Glucosamine inhibits the coaggregation of Candida yeast species with the bacterial strain S. salivarius.

Analízis megjegyzés

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Egyéb megjegyzések

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Lábjegyzet

To see an example of a Certificate of Analysis for this material enter LRAB3705 in the slot below. This is an example certificate only and may not be the lot that you receive.

Biztonsági adatok

• Tárolási osztály kódja: 11 - Combustible Solids
• WGK: WGK 2
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable