Ugrás a tartalomra
Merck

ACOA-RO

Roche

Acetyl-Coenzyme A

85% (Enzymatic and Absorbance), 2% (lithium)

Szinonimák:

Acetyl-Coenzyme A, acetyl-coa

Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez


About This Item

UNSPSC kód:
12352204

leírás

Chemical Formula: C23H35N7O17P3SLi3

Minőségi szint

Teszt

85% (Enzymatic and Absorbance)

form

solid

molekulatömeg

Mr 809.6 (acetyl-CoA)
Mr 827.4 (acetyl-CoA-Li3)

kiszerelés

pkg of 010 mg (10101893001)
pkg of 200 mg (11585371001)
pkg of 050 mg (10101907001)

gyártó/kereskedő neve

Roche

koncentráció

2% (lithium)

tárolási hőmérséklet

2-8°C

Általános leírás

Acetyl-Coenzyme A, trilithium salt

Alkalmazás

Acetyl-Coenzyme A is used to assay CAT enzyme activity in cell extracts using radioisotopes. CAT enzyme activity in cell extracts catalyzes the transfer of acetyl groups from acetylcoenzyme A to chloramphenicol. A number of assays have been developed to measure CAT activity in cell extracts. Acetyl-Coenzyme A has also been used to determine citrate synthase activity.

Biokémiai/fiziológiai hatások

Acetyl-Coenzyme A (Ac-CoA) is the end product of glycolysis and takes part in the Ac-CoA pathway, which is a metabolic pathway for carbon compounds. Ac-CoA is important in cholesterol synthesis. It also takes part in fatty acid biosynthesis and catabolism of polyamines like spermine and spermidine. A low level of Ac-CoA leads to a loss in glial cell and neuronal function. Ketone bodies and triglycerides give rise to Ac-CoA on hydrolysis and this indirectly leads to increased histone acetylation.

Elkészítési megjegyzés

Working solution: Optimal solvent: water or aqueous solution with a weak acidic pH (4 to 5).
Storage conditions (working solution): -15 to -25 °C
50 mg/ml in phosphate buffer, pH 7, is stable for 3 weeks at -15 to -25 °C. Unfrozen solutions should be immediately used.

Egyéb megjegyzések

For life science research only. Not for use in diagnostic procedures.

Tárolási osztály kódja

11 - Combustible Solids

WGK

WGK 1

Lobbanási pont (F)

Not applicable

Lobbanási pont (C)

Not applicable


Analitikai tanúsítványok (COA)

Analitikai tanúsítványok (COA) keresése a termék sarzs-/tételszámának megadásával. A sarzs- és tételszámok a termék címkéjén találhatók, a „Lot” vagy „Batch” szavak után.

Már rendelkezik ezzel a termékkel?

Az Ön által nemrégiben megvásárolt termékekre vonatkozó dokumentumokat a Dokumentumtárban találja.

Dokumentumtár megtekintése

Giosalba Burgio et al.
Biochimica et biophysica acta, 1799(10-12), 671-680 (2010-05-25)
The eukaryotic genome is a highly organized nucleoprotein structure comprising of DNA, histones, non-histone proteins, and RNAs, referred to as chromatin. The chromatin exists as a dynamic entity, shuttling between the open and closed forms at specific nuclear regions and
Jean-Pierre Montmayeur and Johannes le Coutre
Fat Detection-Taste, Texture, and Post Ingestive Effects null
Morten Scheibye-Knudsen et al.
Cell metabolism, 20(5), 840-855 (2014-12-03)
Cockayne syndrome (CS) is an accelerated aging disorder characterized by progressive neurodegeneration caused by mutations in genes encoding the DNA repair proteins CS group A or B (CSA or CSB). Since dietary interventions can alter neurodegenerative processes, Csb(m/m) mice were
Agnieszka Jankowska-Kulawy et al.
Neurochemistry international, 57(7), 851-856 (2010-09-21)
Several pathologic conditions are known to cause thiamine deficiency, which induce energy shortages in all tissues, due to impairment of pyruvate decarboxylation. Brain is particularly susceptible to these conditions due to its high rate of glucose to pyruvate-driven energy metabolism.
Short-term variation of nutritive and metabolic parameters in Temora longicornis females (Crustacea, Copepoda) as a response to diet shift and starvation
Tobias Kreibich
Helgoland Marine Research , 62(3), 241-249 (2008)

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