C4780

Coenzyme A sodium salt hydrate

BioReagent, suitable for cell culture

• Szinonimák: CoA Na₂
• Tapasztalati képlet (Hill-képlet): C₂₁H₃₆N₇O₁₆P₃S · xNa⁺ · yH₂O
• CAS-szám: 55672-92-9
• Molekulatömeg: 767.53 (anhydrous free acid basis)
• EC-szám: 259-747-8
• MDL-szám: MFCD00079020
• UNSPSC kód: 12352205
• PubChem Substance ID: 24892723
• NACRES: NA.75

Tulajdonságok

• biológiai forrás: yeast
• Minőségi szint: 200
• leírás: cofactor for acyl transfer
• termékcsalád: BioReagent
• Teszt: ≥85% (HPLC)
• Forma: powder
• technika/technikák: cell culture | mammalian: suitable
• oldhatóság: water: 50 mg/mL, clear, colorless to faintly yellow
• tárolási hőmérséklet: −20°C
• SMILES string: [Na+].CC(C)(COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)([O-])=O)n2cnc3c(N)ncnc23)C(O)C(=O)NCCC(=O)NCCS
• InChI: 1S/C21H36N7O16P3S.Na/c1-21(2,16(31)19(32)24-4-3-12(29)23-5-6-48)8-41-47(38,39)44-46(36,37)40-7-11-15(43-45(33,34)35)14(30)20(42-11)28-10-27-13-17(22)25-9-26-18(13)28;/h9-11,14-16,20,30-31,48H,3-8H2,1-2H3,(H,23,29)(H,24,32)(H,36,37)(H,38,39)(H2,22,25,26)(H
• Nemzetközi kémiai azonosító kulcs: SYTRWOCXZXQBPW-CLVRNSBASA-M

Leírás

Alkalmazás

Coenzyme A sodium salt hydrate has been used:

• in the branch chain aminotransferase enzymatic assay and protein determination
• in the assay for halogenation of pyrrolyl-S-Bmp1 (an acyl carrier protein (ACP)-thioesterase (TE) di-domain protein) by Bmp2
• as an extracellular coenzyme A (CoA) in in vitro and in vivo experiments to study alternative routes by which cells and organisms can obtain CoA

Biokémiai/fiziológiai hatások

Coenzyme A (CoA) is a ubiquitous cofactor that plays an important role in many metabolic pathways, mainly as acyl-CoA. It is essential for the tricarboxylic acid cycle, and the synthesis and oxidation of fatty acids. CoA facilitates acyl group transfers, especially in fatty acid and lipid metabolism reactions. It is associated with neurodegeneration, autophagy, protein acetylation, and signal transduction.

Minőség

Enzymatically assayed using phosphotransacetylase. Approx. 95% CoA-SH

Biztonsági adatok

• Tárolási osztály kódja: 11 - Combustible Solids
• WGK: WGK 3
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable
• Egyéni védőeszköz: Eyeshields, Gloves, type N95 (US)