A-921

7-Aminoflunitrazepam-d₇ solution

100 μg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant^®

• Tapasztalati képlet (Hill-képlet): C₁₆D₇H₇FN₃O
• CAS-szám: 879894-27-6
• Molekulatömeg: 290.34
• EC-szám: 200-835-2
• MDL-szám: MFCD01861522
• UNSPSC kód: 41116107
• PubChem Substance ID: 329771041
• NACRES: NA.24

Tulajdonságok

• grade: certified reference material
• Minőségi szint: 300
• form: liquid
• Jellemzők: SNAP-N-SPIKE^®, SNAP-N-SHOOT^®
• kiszerelés: ampule of 1 mL
• gyártó/kereskedő neve: Cerilliant^®
• drug control: Narcotic Licence Schedule B (Switzerland)
• koncentráció: 100 μg/mL in acetonitrile
• technika/technikák: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• alkalmazás(ok): clinical testing
• format: single component solution
• tárolási hőmérséklet: 2-8°C
• SMILES string: O=C1CN=C(C2=C([2H])C([2H])=C([2H])C([2H])=C2F)C3=C(C=CC(N)=C3)N1C([2H])([2H])[2H]
• InChI: 1S/C16H14FN3O/c1-20-14-7-6-10(18)8-12(14)16(19-9-15(20)21)11-4-2-3-5-13(11)17/h2-8H,9,18H2,1H3/i1D3,2D,3D,4D,5D
• Nemzetközi kémiai azonosító kulcs: LTCDLGUFORGHGY-AAYPNNLASA-N

Leírás

Általános leírás

This stable-labeled internal standard is suitable for quantitation of 7-aminoflunitrazepam levels in GC/MS or LC/MS methods for clinical toxicology, forensic analysis, urine drug testing, pain prescription monitoring or isotope dilution applications. 7-Aminoflunitrazepam is a major urinary metabolite of flunitrazepam, sold under the trade name Rohypnol. Flunitrazepam is an intermediate-acting benzodiazepine prescribed for the treatment of severe insomnia.

Alkalmazás

• Use in Forensic Toxicology: The application of 7-Aminoflunitrazepam-d7 as an analytical standard in forensic toxicology is suggested due to its stable isotope labeling, enhancing the accuracy of detecting benzodiazepine metabolites in biological samples. This application supports precise quantitative analysis in forensic cases (Decundo et al., 2024).
• Internal Standard for LC-MS/MS: 7-Aminoflunitrazepam-d7 is valuable as an internal standard for LC-MS/MS in the analysis of complex biological matrices. Its use improves the reliability of pharmacokinetic studies of benzodiazepines, providing essential data for both clinical and research settings (Mandal et al., 2024).
• Research in Benzodiazepine Metabolism: High-purity 7-Aminoflunitrazepam-d7 is crucial for the study of benzodiazepine metabolism, particularly in understanding the pharmacokinetic profiles of these drugs. The stable isotope-labeled compound aids in detailed metabolite analysis, contributing to safer drug design and therapeutic monitoring (Johnson et al., 2024).

Jogi információk

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Biztonsági adatok

• Piktogramok: GHS02,GHS07
• Figyelmeztetés: Danger
• Figyelmeztető mondatok: H225,H302 + H312 + H332,H319
• Óvintézkedésre vonatkozó mondatok: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338
• Veszélyességi osztályok: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
• Tárolási osztály kódja: 3 - Flammable liquids
• WGK: WGK 2
• Lobbanási pont (F): 35.6 °F - closed cup
• Lobbanási pont (C): 2 °C - closed cup