QBD10512

Azido-dPEG^®₈-acid

• Szinonimák: Polyethylene glycol
• Tapasztalati képlet (Hill-képlet): C₁₉H₃₇N₃O₁₀
• CAS-szám: 1214319-92-2
• Molekulatömeg: 467.51
• MDL-szám: MFCD21363300
• UNSPSC kód: 12352106
• PubChem Substance ID: 329823934
• NACRES: NA.22

Tulajdonságok

• Teszt: >90%
• form: solid or viscous liquid
• reakcióalkalmasság: reaction type: click chemistry; reagent type: cross-linking reagent; reaction type: click chemistry
• funkcionális csoport: azide; carboxylic acid
• polimer felépítés: shape: linear; functionality: heterobifunctional
• kiszállítva: ambient
• tárolási hőmérséklet: −20°C
• SMILES string: OC(CCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])=O

Leírás

Tulajdonságok és előnyök

The azido-dPEG^®₈ contains an azide function on one end of a single molecular weight dPEG^® spacer (32.2Å) and a reactive group on the other end of the spacer. The dPEG^® spacer is hydrophilic and non-immunogenic and improves the water solubility of the target molecule while reducing the immunogenicity and increasing the hydrodynamic volume of the target. The reactive acid functional group may be activated with 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC) or N,N′-dicyclohexylcarbodiimide (DCC) for conjugation to an amine. The azide group reacts with an alkyne in the well-known click chemistry reaction. The click chemistry reaction proceeds by copper(I) or ruthenium catalysis or in a strain-catalyzed reaction with certain types of alkyne partners.

Jogi információk

Products Protected under U.S. Patents # 7,888,536 B2

dPEG is a registered trademark of Quanta BioDesign

Biztonsági adatok

• Tárolási osztály kódja: 11 - Combustible Solids
• WGK: WGK 3
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable